The role of MSC therapy in attenuating the damaging effects of the cytokine storm induced by COVID-19 on the heart and cardiovascular system

GM Ellison-Hughes, L Colley, KA O'Brien… - Frontiers in …, 2020 - frontiersin.org
… The cytokine storm is not only one of the predominant pathophysiological mechanisms of …
These pathophysiological consequences promote vascular hyperpermeability. Disruption of …

Cytokine storm and neuropathological alterations in patients with neurological manifestations of COVID-19

C Tsagkaris, M Bilal, I Aktar, Y Aboufandi… - Current Alzheimer …, 2022 - ingentaconnect.com
… also shown a high level of IL-6, intrathecal IgG, neurofilament … of COVID-19-associated
cytokine storm. While the short-term … The association of the aforementioned cytokines with the …

Cytokine storm syndrome in SARS-CoV-2 infections: a functional role of mast cells

B Hafezi, L Chan, JP Knapp, N Karimi, K Alizadeh… - Cells, 2021 - mdpi.com
cytokines and eventually the development of cytokine storm … In this review, we present
evidence that a cytokine response … cause the development of cytokine storm syndrome. We also …

Cytokine release syndrome associated with T-cell-based therapies for hematological malignancies: pathophysiology, clinical presentation, and treatment

M Cosenza, S Sacchi, S Pozzi - International journal of molecular …, 2021 - mdpi.com
… large amounts of IL-6 which in turn activates T cells and other immune cells leading to a
cytokine storm (Figure 1). However, the pathophysiology of CRS is still poorly understood. …

From anti-SARS-CoV-2 immune response to the cytokine storm via molecular mimicry

D Kanduc - Antibodies, 2021 - mdpi.com
… mimicry in the cytokine storms associated with severe acute … , can lead to cytokine storms
characterized by diverse disorders … the raging of the cytokine storm that can occur following …

Comparing the cytokine storms of COVID-19 and pandemic influenza

LM Pacheco-Hernández… - … interferon & cytokine …, 2022 - liebertpub.com
… influenza from the perspective of cytokine storms as the driving force underlying morbidity.
Thereby, we analyze similarities and differences in the cytokine profiles of both infections, …

[HTML][HTML] Cytokine storm–based mechanisms for extrapulmonary manifestations of SARS-CoV-2 infection

MDN Avila, R Das, J Kharlyngdoh, E Molina-Jijon… - JCI insight, 2023 - ncbi.nlm.nih.gov
… comparison with rare manifestations of a common cold cytokine storm (16–25), with which it
… have considered cytokine storm to play a leading role. Since the COVID-19 cytokine storm is …

COVID-19 and cytokine storm syndrome: are there lessons from macrophage activation syndrome?

MJ Ombrello, GS Schulert - Translational Research, 2021 - Elsevier
… Beyond the proinflammatory mechanisms implicated in other cytokine storm syndromes,
activation … COVID-19 patients and its specific contribution to pathophysiology are not yet known. …

Coronavirus disease-2019: A review on the disease exacerbation via cytokine storm and concurrent management

H Sunkara, SMR Dewan - International immunopharmacology, 2021 - Elsevier
mechanism of viral cell entry and particularly cytokine storm intending to focus on the importance
of repurposing drugs that target viral cell entry mechanisms … -19 pathophysiology and …

Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
… This concept of a common terminal pathway resulting from diverse pathophysiological
mechanisms can reasonably be extended to other cytokine storm syndromes including COVID-…