… population genetic approaches can contribute greatly to the development of novel methods
to identify causal genetic … In summary, genes associated with complex diseases and traits are …

… origins of the genetic basis of complex diseases, as well as the problems plaguing genetic
… of the issues at the heart of genetic investigations of complex diseases. It has focused on …

… the potential utility of network medicine approaches in human disease. We will do so by
emphasizing the role of multiple –omics approaches to provide insights into complex diseases. …

… We describe a variety of approaches that are currently available… approach to analysis that
systemically addresses the different genetic factors that are likely to underlie complex diseases…

… to the study of complex disease genetics. Admixture linkage disequilibrium (ALD) is created
by the process of admixture and, in recently admixed populations, extends for substantial …

… of genetic variants therein is complex and typically requires further empirical investigation.
In this Perspective, we will describe recent advances at the interface between genetics and …

… variation that is relatively common in the general population. Unfortunately, … few genetic
regions and genes involved in complex diseases have been identified. Completion of the human …

… unique roles in the genetics of complex diseases. In this … the genetics of complex diseases
(Fig. 1), including especially inflammatory bowel diseases (IBD) consisting of Crohn’s disease …

… The objective of this manuscript was to propose a culturally appropriate approach to
disseminate complex disease genetics research findings in small Alaska Native communities. …

… This approach is now being advocated as a model for other complex diseases. However, it
is … Such tight couplings to single genes may be incompatible with the stringent homeostatic …