[HTML][HTML] Potential prospects of nanomedicine for targeted therapeutics in inflammatory bowel diseases

MVA Pichai, LR Ferguson - World journal of gastroenterology: WJG, 2012 - ncbi.nlm.nih.gov
… Due to the potential importance of targeted therapy in IBD, this review is presented to … the
prospects of nanomedicine in the modulation of gene expression and targeted therapeutics in …

Aptamers as targeted therapeutics: current potential and challenges

J Zhou, J Rossi - Nature reviews Drug discovery, 2017 - nature.com
… This Review frames the current challenges and potential of therapeutic aptamers, in
particular RNA aptamers. We highlight more than 25 years' worth of technological advances and …

[HTML][HTML] … tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: potential prospects for combined targeted therapeutics

DB Zimonjic, NC Popescu - … journal of oncology, 2012 - spandidos-publications.com
Therapeutic interventions, which would simultaneously target signaling pathways governing
both DLC1 and MYC functions in hepatocarcinogenesis, could result in progress in the …

New developments in Toll-like receptor targeted therapeutics

DJ Connolly, LAJ O'Neill - Current opinion in pharmacology, 2012 - Elsevier
… The prospect of targeting TLRs in multiple … TLR targeted therapeutics. Plasma membrane
and intracellular localized TLRs currently being considered as potential therapeutic targets are …

Targeted nanodrugs for cancer therapy: prospects and challenges

M Bottini, C Sacchetti, A Pietroiusti… - … of Nanoscience and …, 2014 - ingentaconnect.com
… The recent advent of nanomedicine holds potential to revolutionize cancer therapy. This
innovative … of FDA-approved monoclonal antibodies used as tumor tissue-targeting therapeutics. …

Druggable targets and targeted drugs: enhancing the development of new therapeutics

ML Billingsley - Pharmacology, 2008 - karger.com
… have raised expectations of novel targets for drug discovery and design. … raised the prospects
of highly targeted therapeutics that … However, numerous potentially new targets may not be …

Therapeutic targeting of microRNAs: current status and future challenges

Z Li, TM Rana - Nature reviews Drug discovery, 2014 - nature.com
therapeutic oligonucleotides in vivo. Finally, we review current progress on the clinical
development of miRNA-targeting therapeutics… Finally, we assess potential approaches to improve …

Targeted therapy of cancer: new prospects for antibodies and immunoconjugates

RM Sharkey, DM Goldenberg - CA: a cancer journal for …, 2006 - Wiley Online Library
… Molecular engineering has improved the prospects for such antibody-based therapeutics, …
impede targeting of every cell. Although higher energy beta-emitters have the potential of …

Targeting proteases: successes, failures and future prospects

B Turk - Nature reviews Drug discovery, 2006 - nature.com
… , which makes them potential targets for antidiabetic therapy. … therapeutic potential for DPPIV
inhibitors. The GLP1-stabilizing effect of DPPIV and validation of it as an antidiabetic target

Therapeutic potential of small molecules and engineered proteins

EV Gurevich, VV Gurevich - … -Pharmacology and Therapeutic Potential, 2014 - Springer
… The first steps in targeted engineering of proteins with … of these novel therapeutic agents
with enormous potential: custom-… The prospects of constructing arrestins specifically targeting