… Cytokine storm syndrome (CSS) has generally been … Cytokine storms (CSs) are associated
with various pathologies, … diseases, or following therapeutic interventions. Despite the role of …

… Articles found were assessed as potential reference sources. Also, we searched in … enrolling
potential therapeutic drugs related to pathophysiological mechanisms and cytokine storm. …

… presentation, secretion of cytokines, production of … possible macrophage-mediated
inflammatory responses in SARS-CoV-2 infection and propose potential therapeutic interventions …

… immunity, inhibit the inflammatory cytokine surge, improve … treatment of COVID-19 cytokine
storm focuses primarily on support and symptomatic treatment of inflammation, cytokine storm …

… Treatments that have been shown to alleviate CRS can provide clues to mechanisms
involved in CRS initiation and progression while also revealing potential therapeutic targets [76]. …

… SARS-CoV-2 mediated cytokine storm is associated with the mortality and morbidity of
COVID-19 patients. The key cytokines implicated in the onset of disease severity include TNF-α, …

… cytokine release in response to viral infection, a condition known as cytokine release
syndrome (CRS) or cytokine storm… timed anti-inflammatory therapeutic strategies could improve …

… identify the cytokine storm. In this review, we referred COVID-19 associated cytokine storm as
… patients who are severely ill along with a high concentration of pro-inflammatory cytokines. …

… cytokine storm syndromes, we outline a therapeutic approach that can be generalized across
all forms of cytokine storm, … drivers of disease pathogenesis for each type of cytokine storm. …

… the number of cytokines involved in … cytokine storm development, and therapeutic interventions
that target these cells may be a more feasible approach than targeting specific cytokines. …