Proinflammatory cytokines and treatment of disease

JWM van der Meer, MTE Vogels… - Annals of the New …, 1998 - Wiley Online Library
… Reenforcement of the proinflammatory cytokine response and inhibition of the anti-… aimed
at treatment of infection and neoplastic disease. Inhibition of the proinflammatory response and …

Proinflammatory cytokines in heart disease

CA Dinarello, BJ Pomerantz - Blood purification, 2001 - karger.com
… -based therapies in treating heart disease is great. … for proinflammatory cytokine contribution
to the formation of atherosclerotic lesions. The endothelial layer encounters three cytokine-…

Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases

W Strober, IJ Fuss - Gastroenterology, 2011 - Elsevier
… anti−IL-12p40 was shown to be effective in the treatment of CD, a new set of cytokines, the
Th17 cytokines (IL-17 and IL-23), was shown to function as effectors in various autoimmune …

The paradox of pro-inflammatory cytokines in cancer

CA Dinarello - Cancer and Metastasis Reviews, 2006 - Springer
… -cytokine therapies for the treatment of auto inflammatory as well as autoimmune diseases.
… in a destructive and painful disease process and role of the same cytokine in host defense. …

Treatment of Crohn's disease with recombinant human interleukin 10 induces the proinflammatory cytokine interferon γ

H Tilg, C Van Montfrans, A Van den Ende, A Kaser… - Gut, 2002 - gut.bmj.com
… In the current study, we decided to assess cytokine production by lymphocytes and … study
indicate that IL-10 differently affects the two proinflammatory cytokines TNF-α and IFN-γ, as …

[PDF][PDF] Proinflammatory cytokines in HIV disease-a review and rationale for new therapeutic approaches

NC Connolly, SA Riddler, CR Rinaldo - AIDS Rev, 2005 - researchgate.net
… Antiretroviral drugs currently in use for treating HIV-1 … Proinflammatory cytokines are the
central mediators of both innate and adaptive immunity, and modulation of these cytokines

Effect of hydroxychloroquine treatment on pro-inflammatory cytokines and disease activity in SLE patients: data from LUMINA (LXXV), a multiethnic US cohort

R Willis, AM Seif, G McGwin Jr… - Lupus, 2012 - journals.sagepub.com
… We provide evidence confirming the presence of elevated pro-inflammatory cytokines in …
levels and disease activity. We also demonstrate that HCQ results in decreased disease activity …

Proinflammatory cytokines (TNF-α and IL-6) in Egyptian patients with SLE: its correlation with disease activity

A Sabry, A El-husseini, K Mahmoud, KF Eldahshan… - Cytokine, 2006 - Elsevier
… to the healthy control subjects and these levels are well correlated with SLE disease activity.
In the future targeting these cytokines may provide novel valuable options for treating SLE. …

Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases

JA Smith, A Das, SK Ray, NL Banik - Brain research bulletin, 2012 - Elsevier
… may also reveal new targets in the treatment of neurodegenerative … the treatment of
neurodegenerative diseases. Nonetheless, the volume of evidence linking pro-inflammatory cytokine

The proinflammatory cytokines interleukin-l and tumor necrosis factor and treatment of the septic shock syndrome

CA Dinarello - Journal of Infectious Diseases, 1991 - academic.oup.com
… are the primary proinflammatory cytokines; moreover, these two cytokines act in a …
proinflammatory cytokines, most notably the family of neutrophil and monocyte chemotactic …