Chemosensory dysfunction in COVID-19: integration of genetic and epidemiological data points to D614G spike protein variant as a contributing factor

R Butowt, K Bilinska… - ACS chemical …, 2020 - ACS Publications
… The binding affinity of the RBD in the spike protein of SARS-… of S1-RBD of its spike protein
for hACE2 was estimated to be … we propose that variants of the spike protein with higher RBD …

Chemosensory dysfunction in patients with COVID-19: what do we learn from the global outbreak?

M Zeng, DY Wang, J Mullol, Z Liu - Current Allergy and Asthma Reports, 2021 - Springer
… Three central variants of SARS-CoV-2 … SNP variant of Spike protein (G614) has become
the dominant strain in the pandemic, while the ancestral strain with the Spike protein variant of …

Prevalence of chemosensory dysfunction in COVID-19 patients: a systematic review and meta-analysis reveals significant ethnic differences

CS von Bartheld, MM Hagen… - ACS chemical …, 2020 - ACS Publications
… genetic variants of the SARS-COV-2 virus entry proteins may … differential susceptibility to
chemosensory dysfunctions. It is … to the variation in the prevalence of chemosensory dysfunction. …

Chemosensory dysfunction in neurodegenerative diseases

RL Doty, CH Hawkes - Handbook of clinical neurology, 2019 - Elsevier
… ataxias), the dysfunction is much less than that seen in AD, DS, or PD. The disparity from
DS is interesting since the Fragile X mental retardation protein (FMRP) interacts with the DS …

Chemosensory function and dysfunction

AI Spielman - Critical Reviews in Oral Biology & Medicine, 1998 - journals.sagepub.com
… Most chemosensory complaints have an identifiable cause. … chemosensory mechanisms,
establishing improved diagnostic procedures, and disseminating knowledge on chemosensory

New study on prevalence of anosmia in COVID-19 implicates the D614G virus mutation as a major contributing factor to chemosensory dysfunction

CS von Bartheld, D Mathew, R Butowt - European Archives of Oto-Rhino …, 2021 - Springer
… ), the entry protein to which the viral spike protein binds, has different variants, resulting
in differing virus binding affinities and the frequency of such ACE2 variants is known to differ …

[HTML][HTML] Regional and chronological variation of chemosensory dysfunction in COVID-19: a meta-analysis

JW Kim, SC Han, HD Jo, SW Cho… - Journal of Korean …, 2021 - synapse.koreamed.org
… A previous study revealed the global transition of the SARS-CoV-2 spike protein from the
original D614 to the G614 variant.70 To be specific, through March 1, 2020, the G614 variant

Chemosensory loss in COVID‐19

W Xu, G Sunavala‐Dossabhoy, AI Spielman - Oral diseases, 2022 - Wiley Online Library
… as the virus mutated into different variants. Anosmia and ageusia, … is replete with chemosensory
dysfunctions as a common … UGT2A proteins are found in the nasal epithelium and are …

Association between chemosensory dysfunction and diet quality in United States adults

CR Roxbury, IA Bernstein, SY Lin… - American Journal of …, 2022 - journals.sagepub.com
Background Evidence suggests chemosensory dysfunction (CSD) patients have altered diet,
but population-level evidence assessing diet quality in CSD patients is lacking. Objective …

Interactions of SARS-CoV-2 spike protein and transient receptor potential (TRP) cation channels could explain smell, taste, and/or chemesthesis disorders

H Maaroufi - arXiv preprint arXiv:2101.06294, 2021 - arxiv.org
… that their dysfunction by S protein could explain OTC disorders in COVID-19 disease. …
diverse cellular functions by mediating specific proteinprotein interactions and/or is an …