In order to probe the interaction between tRNA and the tRNA hypermodifying enzyme, tRNA-
guanine transglycosylase (TGT) from Escherichia coli, we have undertaken the generation …

Previously, we have demonstrated that the tRNA-guanine transglycosylase (TGT) from
Escherichia coli is capable of utilizing an in vitro generated minihelix consisting of the …

Revised Manuscript Received February 25, 1993 abstract: tRNA-guanine transglycosylase
(TGT) is the enzyme responsible for the post-transcriptional modification of specific tRNAs …

In eubacteria, the biosynthesis of queuine, a modified base found in the wobble position (#
34) of tRNAs coding for Tyr, His, Asp, and Asn, occurs via a multistep pathway. One of the …

tRNA-guanine transglycosylase (TGT) catalyzes the exchange of queuine (or a precursor)
for guanine 34 in tRNA. The minimal RNA recognition motif for TGT has been found to …

Escherichia coli tRNA-guanine transglycosylase is an enzyme which catalyzes replacement
of guanine (G34) of tRNA (Asp), tRNA (Asn), tRNA (His) and tRNA (Tyr) by free guanine or …

The enzyme tRNA− guanine transglycosylase (TGT, EC 2.4. 2.29) catalyzes a
posttranscriptional transglycosylation reaction involved in the incorporation of the modified …

tRNA–guanine transglycosylase (TGT) is a key enzyme involved in the posttranscriptional
modification of tRNA across the three kingdoms of life. In eukaryotes and eubacteria, TGT is …

A key enzyme involved in the incorporation of the modified base queuine into tRNA (position
34) is tRNA-guanine transglycosylase (TGT). Studies of the recognition of truncated tRNAs …

The modified RNA base queuine [7-(4, 5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-
deazaguanine] is present in tRNA because of a unique base-exchange process catalyzed …