Applications of mass spectrometry for cellular lipid analysis

C Wang, M Wang, X Han - Molecular BioSystems, 2015 - pubs.rsc.org
Mass spectrometric analysis of cellular lipids is an enabling technology for lipidomics, which
is a rapidly-developing research field. In this review, we briefly discuss the principles …

Lipidomics: analysis of the lipid composition of cells and subcellular organelles by electrospray ionization mass spectrometry

B Brügger - Annual review of biochemistry, 2014 - annualreviews.org
Lipidomics aims to quantitatively define lipid classes, including their molecular species, in
biological systems. Lipidomics has experienced rapid progress, mainly because of …

Glycerophospholipid identification and quantitation by electrospray ionization mass spectrometry

PT Ivanova, SB Milne, MO Byrne, Y Xiang… - Methods in …, 2007 - Elsevier
Glycerophospholipids are the structural building blocks of the cellular membrane. In addition
to creating a protective barrier around the cell, lipids are precursors of intracellular signaling …

Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples

X Han, RW Gross - Mass spectrometry reviews, 2005 - Wiley Online Library
Lipidomics, after genomics and proteomics, is a newly and rapidly expanding research field
that studies cellular lipidomes and the organizational hierarchy of lipid and protein …

Mass spectrometry-based shotgun lipidomics–a critical review from the technical point of view

FF Hsu - Analytical and bioanalytical chemistry, 2018 - Springer
Over the past decade, mass spectrometry (MS)-based “shotgun lipidomics” has emerged as
a powerful tool for quantitative and qualitative analysis of the complex lipids in the biological …

Applications of mass spectrometry-based targeted and non-targeted lipidomics

HC Lee, T Yokomizo - Biochemical and biophysical research …, 2018 - Elsevier
Recent advances in mass spectrometry have expanded our knowledge of lipids and lipid
metabolic pathways involved in many (patho) physiological events. Targeted and non …

Multi‐dimensional mass spectrometry‐based shotgun lipidomics and novel strategies for lipidomic analyses

X Han, K Yang, RW Gross - Mass spectrometry reviews, 2012 - Wiley Online Library
Since our last comprehensive review on multi‐dimensional mass spectrometry‐based
shotgun lipidomics (Mass Spectrom. Rev. 24 (2005), 367), many new developments in the …

Selection of internal standards for accurate quantification of complex lipid species in biological extracts by electrospray ionization mass spectrometry—What, how and …

M Wang, C Wang, X Han - Mass spectrometry reviews, 2017 - Wiley Online Library
Lipidomics is rapidly expanding because of the great facilitation of recent advances in, and
novel applications of, electrospray ionization mass spectrometry techniques. The greatest …

Glycerolipid and cholesterol ester analyses in biological samples by mass spectrometry

RC Murphy, TJ Leiker, RM Barkley - … Acta (BBA)-Molecular and Cell Biology …, 2011 - Elsevier
Neutral lipids are a diverse family of hydrophobic biomolecules that have important roles in
cellular biochemistry of all living species but have in common the property of charge …

Lipidomics: a mass spectrometry based systems level analysis of cellular lipids

PT Ivanova, SB Milne, DS Myers, HA Brown - Current opinion in chemical …, 2009 - Elsevier
Lipidomics is a logical outcome of the history and traditions of lipid biochemistry and
advances in mass spectrometry are at the heart of a renaissance in understanding the roles …