B cells in Sjögren's syndrome: from pathophysiology to diagnosis and treatment

D Cornec, V Devauchelle-Pensec, GJ Tobón… - Journal of …, 2012 - Elsevier
Primary Sjögren's syndrome (pSS) is a chronic autoimmune systemic disease, characterized
by a lymphoplasmocytic infiltration and a progressive destruction of salivary and lachrymal …

B cells in Sjögren's syndrome: from pathophysiology to therapeutic target

J Mielle, A Tison, D Cornec, L Le Pottier, C Daien… - …, 2021 - academic.oup.com
Biological abnormalities associated with B lymphocytes are a hallmark of patients with
primary Sjögren's syndrome. Those patients present abnormal distribution of B lymphocytes …

B cells in the pathogenesis of primary Sjögren syndrome

G Nocturne, X Mariette - Nature Reviews Rheumatology, 2018 - nature.com
Primary Sjögren syndrome (pSS) is a prototypical autoimmune disease. The involvement of
B cells in the pathogenesis of pSS has long been suspected on the basis of clinical …

Immunobiology of T cells in Sjögren's syndrome

Y Yao, JF Ma, C Chang, T Xu, CY Gao… - Clinical Reviews in …, 2021 - Springer
Sjögren's syndrome (SjS) is a systemic autoimmune disease marked by xerostomia (dry
mouth), keratoconjunctivitis sicca (eye dryness), and other systematic disorders. Its …

[HTML][HTML] B cell dysregulation in primary Sjögren's syndrome: a review

HM Ibrahem - Japanese Dental Science Review, 2019 - Elsevier
Primary Sjögren's syndrome is a chronic autoimmune disorder of unknown etiology and is
characterized by progressive focal lymphocytic infiltration of the lacrimal and salivary glands …

Sjögren's syndrome—A plethora of clinical and immunological phenotypes with a complex genetic background

R Jonsson, AI Bolstad, KA Brokstad… - Annals of the New York …, 2007 - Wiley Online Library
Primary Sjögren's syndrome is a complex autoimmune disorder, considered to represent an
ideal disease with which to study the mechanisms underlying autoimmunity because its …

[PDF][PDF] Sjögren's syndrome: one year in review 2022

V Manfrè, LG Chatzis, G Cafaro, S Fonzetti… - Clin Exp …, 2022 - clinexprheumatol.org
Primary Sjögren's syndrome (pSS) is a complex disabling systemic autoimmune disorder.
The hallmark of pSS is the T-cell-mediated hyperactivation of B-cells, evolving from …

Sjögren's syndrome

CP Mavragani, GE Fragoulis… - The Autoimmune …, 2014 - Elsevier
Sjögren's syndrome (SjS) is a systemic autoimmune disease, characterized by the presence
of periductal lymphocytic infiltrations in salivary and lachrymal glands resulting in oral and …

T cells in primary Sjögren's syndrome: targets for early intervention

GM Verstappen, FGM Kroese, H Bootsma - Rheumatology, 2021 - academic.oup.com
A histologic hallmark of primary SS (pSS) is lymphocytic infiltration of the salivary and
lacrimal glands, in particular by CD4+ T and B cells. In the early stages of the disease …

Exploiting the role of T cells in the pathogenesis of Sjögren's syndrome for therapeutic treatment

Q An, J Zhao, X Zhu, B Yang, Z Wu, Y Su… - Frontiers in …, 2022 - frontiersin.org
Sjögrens syndrome (SS) is caused by autoantibodies that attack proprioceptive salivary and
lacrimal gland tissues. Damage to the glands leads to dry mouth and eyes and affects …