Chromosomes have been isolated directly from cells in metaphase for study under the
electron microscope by spreading on a Langmuir trough, followed by critical point drying …

Whole mount metaphase chromosomes, from cultured L cells, have been centrifuged onto
grids and examined by electron microscopy. Compact and dispersed chromosome forms …

The relationship between the surface protuberances of mitotic chromosomes isolated from
HeLa cells and the underlying fiber organization was investigated by scanning electron …

Interphase and metaphase chromosomes have been isolated by spreading unfixed cells on
the Langmuir trough, followed by critical point drying. Both types of chromosomes prove to …

Human metaphase chromosomes were processed with a 3% glutaraldehyde‐tannic acid
technique and examined in a scanning electron microscope at 20 kV either without added …

HeLa metaphase chromosomes were exammed by means of “in lens” field emission
scanning electron microscopy, which permits high resolution detection of uncoated …

The development of procedures for the isolation of unfixed metaphase chromosomes has
made feasible a direct analysis of their morphology. Wholemount stereo electron microscopy …

We have performed a very extensive electron microscopy investigation of the chromatin
structures extruded from partially denatured metaphase chromosomes from HeLa cells …

Stereo electron microscopy was employed to examine thin sections of Chinese hamster
ovary metaphase chromosomes in situ and of chromosomes released from Chinese hamster …

Previous studies of the structure of metaphase chromosomes have relied heavily on electron
micrography and have revealed the existence of a 10-nm unit fiber that is thought to …