Calcification of bioprosthetic heart valves fabricated from glutaraldehyde-pretreated bovine
pericardium has not been investigated. The objectives of this study were to characterize …

Calcification, the major cause of bioprosthetic heart valve failures, is a serious clinical
problem with uncertain pathogenesis. The objectives of the present study were to define the …

Gross, histologic and ultrastructural studies were made of 14 porcine valve bioprostheses
that were found to contain calcific deposits at the time of removal either at reoperation (13 …

A major problem with cardiac bioprosthesis is the calcification of the tissue used in their
manufacture, an event which may be promoted by multiple factors. A subcutaneously …

The principal cause of the clinical failure of bioprosthetic heart valves fabricated from
glutaraldehyde‐pretreated porcine aortic valves is calcification. Other prostheses composed …

Calcification limits the long-term success of heart valve bioprostheses fabricated from
glutaraldehyde cross-linked porcine aortic valves. The pathophysiology of calcification of …

Calcification is the principal cause of failure of tissue-derived cardiac valve replacements
pretreated with glutaraldehyde (GLUT). The objective of this study was to determine the role …

To study the process of calcification in bioprostheses, 108 glutaraldehyde-treated porcine
aortic valve leaflets were implanted subcutaneously in rabbits and removed 1 day to 6 …

To determine the incidence and extent of calcification of implanted glutaraldehyde-treated
porcine prosthetic heart valves, 82 valves explanted from 73 patients were examined for …

Bioprosthetic cardiac valve calcification is a frequent complication after long-term valve
replacement. In this study the authors sought to examine the biologic determinants of this …