Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease

DS Knopman, CR Jack Jr, HJ Wiste, SD Weigand… - Neurology, 2012 - AAN Enterprises
Objective: Recommendations for the diagnosis of preclinical Alzheimer disease (AD) have
been formulated by a workgroup of the National Institute on Aging and Alzheimer's …

An operational approach to National Institute on Aging–Alzheimer's Association criteria for preclinical Alzheimer disease

CR Jack Jr, DS Knopman, SD Weigand… - Annals of …, 2012 - Wiley Online Library
Objective: A workgroup commissioned by the Alzheimer's Association (AA) and the National
Institute on Aging (NIA) recently published research criteria for preclinical Alzheimer disease …

NIA-AA staging of preclinical Alzheimer disease: discordance and concordance of CSF and imaging biomarkers

SJB Vos, BA Gordon, Y Su, PJ Visser, DM Holtzman… - Neurobiology of …, 2016 - Elsevier
Abstract The National Institute of Aging and Alzheimer's Association (NIA-AA) criteria for
Alzheimer disease (AD) treat neuroimaging and cerebrospinal fluid (CSF) markers of AD …

NIA‐AA Alzheimer's disease framework: clinical characterization of stages

RC Petersen, HJ Wiste, SD Weigand… - Annals of …, 2021 - Wiley Online Library
Background To operationalize the National Institute on Aging–Alzheimer's Association (NIA‐
AA) Research Framework for Alzheimer's Disease 6‐stage continuum of clinical progression …

Absence of cognitive impairment or decline in preclinical Alzheimer's disease

WP Goldman, JL Price, M Storandt, EA Grant… - Neurology, 2001 - AAN Enterprises
Objective: To determine whether clinically nondemented elderly individuals with
pathologically confirmed preclinical AD are characterized by cognitive decline as measured …

Prevalence of preclinical Alzheimer disease: Comparison of current classification systems

S Kern, H Zetterberg, J Kern, A Zettergren, M Waern… - Neurology, 2018 - AAN Enterprises
Objective To determine the prevalence of preclinical Alzheimer disease (AD) according to
current classification systems by examining CSF from a representative general population …

Mild cognitive impairment due to Alzheimer disease in the community

RC Petersen, P Aisen, BF Boeve, YE Geda… - Annals of …, 2013 - Wiley Online Library
Objective The newly proposed National Institute on Aging–Alzheimer's Association (NIA‐AA)
criteria for mild cognitive impairment (MCI) due to Alzheimer disease (AD) suggest a …

The new Alzheimer's criteria in a naturalistic series of patients with mild cognitive impairment

S Galluzzi, C Geroldi, R Ghidoni, B Paghera… - Journal of …, 2010 - Springer
To test the validity of the new diagnostic criteria for Alzheimer's disease (AD) in a naturalistic
series of patients with mild cognitive impairment (MCI). Ninety consecutive MCI patients …

Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later

CM Roe, AM Fagan, EA Grant, J Hassenstab… - Neurology, 2013 - AAN Enterprises
Objectives: We compared the ability of molecular biomarkers for Alzheimer disease (AD),
including amyloid imaging and CSF biomarkers (Aβ42, tau, ptau181, tau/Aβ42 …

Determining clinically meaningful decline in preclinical Alzheimer disease

PS Insel, M Weiner, RS Mackin, E Mormino, YY Lim… - Neurology, 2019 - AAN Enterprises
Objective To determine the time required for a preclinical Alzheimer disease population to
decline in a meaningful way, use estimates of decline to update previous clinical trial design …