Publisher Summary The electron micrographs of the cell nucleus and chromosomes provide
at first sight a confusing and not very informative picture. The reasons for this are not …

Chromosomes consist of single DNA‐histone fibres (with non‐histone protein and RNA in
the active regions) that are packed by folding or coiling into fibres which can be classified …

Thin sections of the testicular follicles of the grasshopper Laplatacris dispar were studied
under the electron microscope. In the primary spermatocytes, during meiotic prophase, three …

There now seems to be little doubt that DNA in the nucleus of eukaryotic cells is in the form
of very long, continuous molecules, probably thousands of times as long as the largest …

Nucleohistone is probably the basic substance in the chromosomes of higher organisms.
The X-ray diffraction patterns of whole nuclei and nucleohistone extracted from them are …

It is not irrelevant, in the phase of the Symposium that is concerned with the cytological
aspects of nucleic acids and nucleoproteins, to consider how they become" cytological." The …

Chromatin prepared by brief digestion of nuclei with micrococcal nuclease, and extracted in
0.2 mM EDTA, appears in the electron microscope as filaments of about 100 A diameter …

The degree of chromatin condensation in isolated rat liver nuclei and chicken erythrocyte
nuclei was studied by phase-contrast microscopy as a function of solvent pH, K+ and Mg++ …

The nucleosome is the universal protein/DNA element repeated throughout the chromatin of
eukaryotic cells (Kornberg 1977; McGhee and Felsenfeld 1980). Presumably as a …

Publisher Summary This chapter discusses the stereoscopic electron microscopy of
chromosomes. The studies on the higher order structure of chromosomes suggest that …