Recent experimental and clinical studies have placed new emphasis on the role of
angiogenesis in chronic inflammatory disease. Vascular endothelial growth factor (VEGF) …

Chapter Summary The expansion of the synovial lining of joints in rheumatoid arthritis (RA)
and the subsequent invasion by the pannus of underlying cartilage and bone necessitate an …

Objective To investigate the regulation of expression of the angiogenic cytokine vascular
endothelial growth factor (VEGF) in rheumatoid arthritis (RA), in order to determine whether …

Angiogenesis is the formation of new blood vessels from existing vessels. During RA new
blood vessels can maintain the chronic inflammatory state by transporting inflammatory cells …

Rheumatoid arthritis (RA) is a chronic destructive musculo-skeletal disorder, associated with
thickening of the synovial membrane lining the joints, inflammation and hyperproliferation of …

RHEUMATOID arthritis (RA) is characterized by peripheral joint inflammation, which results
from the malign growth of synovial cells as a pannus overlaying and destroying cartilage …

OBJECTIVE: We evaluated the effect of direct angiogenesis inhibition in synovium of
patients with rheumatoid arthritis (RA), using a soluble vascular endothelial growth factor …

Angiogenesis is central to the development and perpetuation of rheumatoid synovitis.
Vascular endothelial growth factor (VEGF), the main mediator of angiogenesis, is found in …

Objective To examine the localization and role of vascular endothelial growth factor (VEGF),
an endothelial cell specific mitogen, in rheumatoid arthritis (RA). Methods …

Vascular endothelial growth factor (VEGF) is a potent inducer of angiogenesis and is
constitutively expressed in the synovium of rheumatoid arthritis (RA). Over‐expression of …