Primary glioblastoma multiforme (GBM), in contrast with secondary GBM, has been
associated with the presence of EGFR amplification and absence of p53 mutation. In this …

Glioblastoma multiforme (GBM) can be divided into genetic subsets: approximately one‐
third of GBM, primarily in older adults, have EGFR amplification; another one‐third, primarily …

In Singapore astrocytic tumours occur in only 25% of patients with primary brain tumours
compared to 40–60% in other series. Glioblastoma multiforme arises either de novo as a …

Glioblastoma multiforme (GBM) carries a dismal prognosis. However, a range of survival
times exists, and parameters that define prognostic groups may help to optimize treatment …

BACKGROUND In contrast to oligodendrogliomas, molecular predictors of prognosis have
not been consistently found in glioblastomas. However, genetic studies show that …

One of the hallmarks of glioblastoma is its inherent tendency to recur. At this point patients
with relapsed GBM show a survival time of only few months. The molecular basis of the …

Purpose: Two clinical-molecular glioblastoma subtypes have been described:“primary”
glioblastomas arise de novo in older patients and often overexpress epidermal growth factor …

Glioblastoma multiforme (GBM) frequently involves amplification and alteration of the
epidermal growth factor receptor (EGFR) gene, resulting in overexpression of varied …

Glioblastoma (GBM) is the most common primary brain tumor in adults and often has
amplification of the epidermal growth factor receptor (EGFR) gene. The value of EGFR as a …

The median survival time of patients with glioblastoma multiforme (GBM) is 12months, and
only 3–5% of patients survive longer than 3years. We performed histomorphological and …