Background: Sickle cell disease hemoglobinopathy gets inherited in autosomal recessive
pattern. In sickle cell disease substitution of amino acid valine for glutamic acid at the sixth …

Background: Sickle cell anaemia is a major genetic disease in India that presents major
challenges to our health care systems. Aim and Objective: The aim of this study was to …

Hematological profile of total 1260 individuals were tested for Sickle Cell Disease who
attended CIMS OPD, Bilaspur during a period of May 2008 to October 2009 is presented …

Sickle cell disease is caused by Mutations in the HBB gene. Hemoglobin consists of four
protein subunits, typically, two subunits called alpha-globin and two subunits called beta …

Our objective was to find out prevalence of sickle cell anemia among the population of three
districts (Kanker, Dantewada and Raigarh) of Chhattisgarh with clinical and hematological …

ABSTRACT Background: Sickle Cell Disorder (SCD) is a major health problem in India. After
introduction of High-Performance Liquid Chromatography (HPLC) in MKCG Medical …

Background: Sickle cell disorders are structural hemoglobinopathies, rendering red blood
cells sickle shaped, less deformable and sticky leading to microvascular vaso-occlusion and …

Introduction: Sickle hemoglobin is the most common pathological hemoglobin mutation
worldwide in which upon deoxygenation RBCs convert into sickle form. Heterozygotes (AS) …

Sickle cell disease (SCD) is the commonest abnormal hemoglobin in the world. The present
study evaluated the SCD in state of Chhattisgarh. The study was conducted in Center for …

Background: Sickle cell disease or sickle cell anemia is a hereditary genetic disease that is
characterized by the presence of abnormal crescent-shaped red blood cells …