Relationship Between Nonsteroidal Anti-Inflammatory Drugs and Bone-Healing After Fracture or Orthopaedic Surgery

T Bigler, E Weidman-Evans… - JBJS Journal of …, 2018 - journals.lww.com
Inflammation is a complex physiologic response with various theoretical effects on the bone-
healing process. Retrospective studies show conflicting results: some cases demonstrate …

Nonsteroidal anti-inflammatory drugs and bone-healing: a systematic review of research quality

A Marquez-Lara, ID Hutchinson, F Nuñez Jr… - JBJS …, 2016 - journals.lww.com
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are often avoided by
orthopaedic surgeons because of their possible influence on bone-healing. This belief …

The effect of nonsteroidal anti-inflammatory drug administration on acute phase fracture-healing: a review

AP Kurmis, TP Kurmis, JX O'Brien, T Dalén - JBJS, 2012 - journals.lww.com
Background: The analgesic efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) is well
established, and these agents often form an integral part of posttraumatic pain management …

Do nonsteroidal anti‐inflammatory drugs affect bone healing? A critical analysis

I Pountos, T Georgouli, GM Calori… - The Scientific World …, 2012 - Wiley Online Library
Nonsteroidal anti‐inflammatory drugs (NSAIDs) play an essential part in our approach to
control pain in the posttraumatic setting. Over the last decades, several studies suggested …

The effect of nonsteroidal anti-inflammatory drugs on bone healing in humans: a qualitative, systematic review

A Borgeat, C Ofner, A Saporito, M Farshad… - Journal of clinical …, 2018 - Elsevier
Study objective Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in
postoperative pain management. While an increasing number of in vitro and animal studies …

The effect of nonsteroidal anti-inflammatory drugs on tissue healing

MR Chen, JL Dragoo - Knee Surgery, Sports Traumatology, Arthroscopy, 2013 - Springer
Abstract Purpose Non-selective (NSAIDs) and selective (COX-2) nonsteroidal anti-
inflammatory drugs are commonly used for their analgesic and anti-inflammatory effects …

Effects of nonsteroidal anti-inflammatory drugs on bone formation and soft-tissue healing

LE Dahners, BH Mullis - … -Journal of the American Academy of …, 2004 - journals.lww.com
Nonsteroidal anti-inflammatory drugs continue to be prescribed as analgesics for patients
with healing fractures even though these drugs diminish bone formation, healing, and …

Positives and negatives of nonsteroidal anti-inflammatory drugs in bone healing: the effects of these drugs on bone repair

B Lisowska, D Kosson, K Domaracka - Drug design, development …, 2018 - Taylor & Francis
Tissue damage following injury triggers the processes of coagulation, inflammation and
healing. In tissues surrounding the bone, the result of the healing process is a scar, while …

Non-steroidal anti-inflammatory drugs in orthopaedic and perioperative practice

W Khan, M Al-Rashid… - Journal of Perioperative …, 2009 - journals.sagepub.com
Non-steroidal anti-inflammatory drugs are powerful and effective anti-inflammatory,
analgesic and anti-pyretic drugs. They are routinely used in orthopaedic conditions and in …

Use of NSAIDs in traumatology

NF Espinosa, B Uebelhart, S Abrassart - Revue Medicale Suisse, 2014 - europepmc.org
In traumatology, non-steroidal anti-inflammatory drugs (NSAIDs) are widely used, due to
their efficacy in controlling pain and safety profile. Nonetheless, experimental and …