Spatial and temporal activity patterns of olfactory bulb projection neurons underlie the initial
representations of odors in the brain. However, olfactory perception ultimately requires the …

In primary sensory cortices, there are two main sources of excitation: afferent sensory input
relayed from the periphery and recurrent intracortical input. Untangling the functional roles of …

The olfactory cortex encompasses several anatomically distinct regions each hypothesized
to provide differential representation and processing of specific odors. Studies exploring …

The mammalian piriform cortex receives direct synaptic input from the olfactory bulb and is
likely the locus for the formation of odor percept. It remains unclear how individual cortical …

The properties of cortical circuits underlying central representations of sensory stimuli are
poorly understood. Here we use in vivo cell-attached and whole-cell voltage-clamp …

Natural odors, generally composed of many monomolecular components, are analyzed by
peripheral receptors into component features and translated into spatiotemporal patterns of …

Odors activate distributed ensembles of neurons within the piriform cortex, forming cortical
representations of odor thought to be essential to olfactory learning and behaviors. This odor …

Highlights•The glomerular organization in the mammalian olfactory bulb is differentially
transformed in higher-order olfactory areas.•The microcircuitry of the piriform cortex enables …

In awake rodents, the neural representation of olfactory information in the olfactory bulb is
largely dependent on brain state and behavioral context. Learning-modified neural plasticity …

Current models of odor discrimination in mammals involve molecular feature detection by a
large family of diverse olfactory receptors, refinement of molecular feature extraction through …