A comparative proteome analysis of human metaphase chromosomes between a typical
epithelial‐like cell, HeLa S3, and a lymphoma‐type cell, BALL‐1, was performed. One …

DNA is packaged as chromatin in the interphase nucleus. During mitosis, chromatin fibers
are highly condensed to form metaphase chromosomes, which ensure equal segregation of …

We have presented a structural model of the chromosome based on its constituent proteins.
Development of a method of mass isolation for intact human metaphase chromosomes and …

Chromosomal nonhistone proteins have important roles in mitotic chromosome formation
and dynamics. In order to identify novel abundant proteins with a potential involvement in …

A large amount of metaphase chromosomes were isolated from synchronized human cell
lines by a polyamine procedure. All the chromosomal proteins extracted by an acetic acid …

Mitotic chromosomes are the iconic structures into which the genome is packaged to ensure
its accurate segregation during mitosis. Although they have appeared on countless journal …

We have examined the metaphase chromosomal localization of 15 proteins that have
previously been described as involved in mammalian chromatin modification and/or …

Recent studies have revealed the importance of Ki-67 and the chromosome periphery in
chromosome structure and segregation, but little is known about this elusive chromosome …

Human karyotype is usually studied by classical cytogenetic (banding) techniques. To
perform it, one has to obtain metaphase chromosomes of mitotic cells. This leads to the …

The three-dimensional (3D) organization of the chromosomal fiber in the human interphase
nucleus is an important but poorly understood aspect of gene regulation. Here we …