Five adult male rhesus monkeys were continuously infused for 56 dayswith 25 μg/day of
GnRH agonist (Wy-40972; Ag) using an implanted osmotic pump. Bioassayable serum …

Constant infusion of GnRH agonist (GnRH-A) leads to far greater suppression of
spermatogenesis and gonadotropins in the monkey than its intermittent administration. We …

Three adult male rhesus monkeys were treated for 20 weeks with a gonadotropin-releasing
hormone (GnRH) agonist (Ag; Wy-40972; Wyeth Laboratories, Philadelphia, PA) using …

Chronic treatment with agonist analogs of GnRH results in reversible oligospermia i man,
but leads to impotence and decreased libido due to a concomitant fall in serum testosterone …

Constant infusion of gonadotropin-releasing hormone agonist (GnRH-A) in the rhesus
monkey leads to far greater suppression of spermatogenesis than its intermittent …

We reported previously that after a single injection of a gonadotrophin-releasing hormone
(GnRH) antagonist to male monkeys, exogenous GnRH stimulated LH secretion in a time …

We examined the effect of continuous sc infusion of a GnRH agonist (Ag) and testosterone
(T) supplementation on spermatogenesis and the potential fertilizing capacity of sperm in 15 …

The effects of a potent gonadotrophin-releasing hormone (GnRH) antagonist,(N-Ac-dp-Cl-
Phe 1, 2, d-Trp 3, d-Arg 6, d-Ala 10)-GnRH (Org 30276), on pituitary and testicular function of …

Plasma levels of radioimmunoreactive LH, FSH, and testosterone (T) were assayed before
and after administration of synthetic gonadotropin-releasing hormone (GnRH) to five chair …

Synthetic long-acting agonistic analogs of GnRH both stimulate and paradoxically inhibit
gonadotropin secretion in male animals and humans. To characterize the stimulatory and …