Since their discovery at the turn of the century by Ramon y Cajal (1), dendritic spines have
fascinated scientists by their unusual structure and by their likely role in cognitive functions …

▪ Abstract Spines are neuronal protrusions, each of which receives input typically from one
excitatory synapse. They contain neurotransmitter receptors, organelles, and signaling …

Dendritic spines are cellular microcompartments that are isolated from their parent dendrites
and neighboring spines. Recently, imaging studies of spine Ca2+ dynamics have revealed …

The ability to monitor ongoing changes in the shape of dendritic spines has important
implications for the understanding of the functional correlates of the great variety of shapes …

The recent use of novel high‐resolution imaging methods of living neurons in vitro has led to
a change in the view of the dendritic spine, from a stable, long‐term memory storage device …

Dendritic spines are tiny protrusions on dendritic shafts where most excitatory synapses are
located. Recent advances in imaging technologies have given us great insight into the …

Dendritic spines are tiny, specialized protoplasmic protuberances that cover the surface of
many neurons. First described by Ramon y Cajal (199 1) in light microscopic studies of …

Although dendritic spines are thought to play an important role in synaptic transmission and
plasticity, their function remains unknown. Theoretical investigations of spine function have …

A leading neurobiologist explores the fundamental function of dendritic spines in neural
circuits by analyzing different aspects of their biology, including structure, development …

Dendritic spines occupy a strategic position in the central nervous system, yet their function
is still under debate. Over the past decades, many hypotheses have been put forward to …