K Leiderman, AL Fogelson - … medicine and biology: a journal of …, 2011 - academic.oup.com
The body's response to vascular injury involves two intertwined processes: platelet aggregation and coagulation. Platelet aggregation is a predominantly physical process …
A comprehensive understanding of thrombus formation as a physicochemical process that has evolved to protect the integrity of the human vasculature is critical to our ability to predict …
Vascular injury triggers two intertwined processes, platelet deposition and coagulation, and can lead to the formation of an intravascular clot (thrombus) that may grow to occlude the …
K Rana, KB Neeves - Blood reviews, 2016 - Elsevier
Blood flow regulates coagulation and fibrin formation by controlling the transport, or mass transfer, of zymogens, co-factors, enzymes, and inhibitors to, from, and within a growing …
Computational models of various facets of hemostasis and thrombosis have increased substantially in the last decade. These models have the potential to make predictions that …
Thrombosis is a life-threatening clinical condition characterized by the obstruction of blood flow in a vessel due to the formation of a large thrombus. The pathogenesis of thrombosis is …
D Basmadjian - Annals of biomedical engineering, 1990 - Springer
The paper presents a mathematical analysis of the contributions of flow and mass transport to a single reactive event at a blood vessel wall. The intent is to prepare the ground for a …
FI Ataullakhanov, MA Panteleev - Pathophysiology of haemostasis and …, 2006 - karger.com
Over the last two decades, mathematical modeling has become a popular tool in study of blood coagulation. The in silico methods were able to yield interesting and significant results …
Z Xu, M Kamocka, M Alber… - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
In addition to descriptive biological models, many computational models have been developed for hemostasis/thrombosis that provide quantitative characterization of thrombus …