Gas plasma-oxidized liquids for cancer treatment: preclinical relevance, immuno-oncology, and clinical obstacles

E Freund, S Bekeschus - IEEE Transactions on Radiation and …, 2020 - ieeexplore.ieee.org
Gas plasmas, often referred to as cold physical plasma, are currently being investigated for
their potential to serve as anticancer agents. Along similar lines, gas plasma-oxidized liquids …

[HTML][HTML] Medical gas plasma technology: Roadmap on cancer treatment and immunotherapy

S Bekeschus - Redox Biology, 2023 - Elsevier
Despite continuous therapeutic progress, cancer remains an often fatal disease. In the early
2010s, first evidence in rodent models suggested promising antitumor action of gas plasma …

Plasma-treated solutions (PTS) in cancer therapy

H Tanaka, S Bekeschus, D Yan, M Hori, M Keidar… - Cancers, 2021 - mdpi.com
Simple Summary Cold physical plasma is a partially ionized gas generating various reactive
oxygen and nitrogen species (ROS/RNS) simultaneously. ROS/RNS have therapeutic …

Plasma-conditioned liquids as anticancer therapies in vivo: Current state and future directions

X Solé-Martí, A Espona-Noguera, MP Ginebra, C Canal - Cancers, 2021 - mdpi.com
Simple Summary During the last decade, cold atmospheric plasmas (CAP) have been
broadly investigated for their therapeutic effect against cancer. CAP sources can be used to …

Cancer treatment with gas plasma and with gas plasma–activated liquid: Positives, potentials and problems of clinical translation

JC Harley, N Suchowerska, DR McKenzie - Biophysical reviews, 2020 - Springer
Gas plasmas, created in atmospheric pressure conditions, both thermal (hot) and non-
thermal (cold) are emerging as useful tools in medicine. During surgery, hot gas plasmas …

Conductive Gas Plasma Treatment Augments Tumor Toxicity of Ringer's Lactate Solutions in a Model of Peritoneal Carcinomatosis

L Miebach, E Freund, AL Cecchini, S Bekeschus - Antioxidants, 2022 - mdpi.com
Reactive species generated by medical gas plasma technology can be enriched in liquids
for use in oncology targeting disseminated malignancies, such as metastatic colorectal …

The emerging role of gas plasma in oncotherapy

X Dai, K Bazaka, DJ Richard, ERW Thompson… - Trends in …, 2018 - cell.com
Atmospheric pressure gas plasmas are emerging as a promising treatment in cancer that
can supplement the existing set of treatment modalities and, when combined with other …

Medical gas plasma treatment in head and neck cancer—challenges and opportunities

J Berner, C Seebauer, SK Sagwal, L Boeckmann… - Applied Sciences, 2020 - mdpi.com
Despite progress in oncotherapy, cancer is still among the deadliest diseases in the Western
world, emphasizing the demand for novel treatment avenues. Cold physical plasma has …

Reactive oxygen species from non-thermal gas plasma (CAP): implication for targeting cancer stem cells

A Babajani, A Eftekharinasab, S Bekeschus… - Cancer Cell …, 2024 - Springer
Cancer remains a major global health challenge, with the persistence of cancer stem cells
(CSCs) contributing to treatment resistance and relapse. Despite advancements in cancer …

[PDF][PDF] Perspectives of plasma-treated solutions as anticancer drugs

P Attri, A Bogaerts - Anti-Cancer Agents in Medicinal …, 2019 - nano.uantwerpen.be
In 2018, there were an estimated 9.6 million deaths from cancers and 18.1 million new
cancer cases reported [1]. Unfortunately, the classical cancer treatments, such as …