The hemostatic response involves blood coagulation and platelet aggregation to stop blood
loss from an injured blood vessel. The complexity of these processes make it difficult to intuit …

Platelets upregulate the generation of thrombin and reinforce the fibrin clot which increases
the incidence risk of venous thromboembolism (VTE). However, the role of platelets in the …

In the last decade numerous mathematical models have been formulated to investigate
specific components of the clotting system such as the tissue factor pathway of coagulation …

The body's response to vascular injury involves two intertwined processes: platelet
aggregation and coagulation. Platelet aggregation is a predominantly physical process …

Thrombosis is a life-threatening clinical condition characterized by the obstruction of blood
flow in a vessel due to the formation of a large thrombus. The pathogenesis of thrombosis is …

Modeling thrombus growth in pathological flows allows evaluation of risk under patient-
specific pharmacological, hematological, and hemodynamical conditions. We have …

A comprehensive understanding of thrombus formation as a physicochemical process that
has evolved to protect the integrity of the human vasculature is critical to our ability to predict …

The paper presents a mathematical analysis of the contributions of flow and mass transport
to a single reactive event at a blood vessel wall. The intent is to prepare the ground for a …

Vascular injury triggers two intertwined processes, platelet deposition and coagulation, and
can lead to the formation of an intravascular clot (thrombus) that may grow to occlude the …

A two-dimensional multiscale model is introduced for studying formation of a thrombus (clot)
in a blood vessel. It involves components for modelling viscous, incompressible blood …