Conspectus Lipids play critical structural and functional roles in the regulation of cellular
homeostasis, and it is increasingly recognized that the disruption of lipid metabolism or …

Lipids and metabolites are of interest in many clinical and research settings because it is the
metabolome that is increasingly recognized as a more dynamic and sensitive molecular …

Lipids are vital biological molecules and play multiple roles in cellular function of
mammalian organisms such as cellular membrane anchoring, signal transduction, material …

Recent advances in mass spectrometry have expanded our knowledge of lipids and lipid
metabolic pathways involved in many (patho) physiological events. Targeted and non …

The objective of this review is to provide a comprehensive summary of the latest
methodological advancements and emerging patterns in utilizing lipidomics in clinical …

Multidimensional mass spectrometry-based shotgun lipidomics (MDMS-SL) has become a
foundational analytical technology platform among current lipidomics practices due to its …

Lipids have been analyzed in applications including drug discovery, disease etiology
elucidation, and natural products. The chemical and structural diversity of lipids requires a …

Conspectus Lipids have pivotal roles in many biological processes, including energy
storage, signal transduction, and plasma membrane formation. A disruption of lipid …

Highlights•The extreme diversity of the lipidome poses a significant analytical challenge.•A
variety of mass spectrometry-based approaches exist for the analysis of lipids.•Combining …

One decade after the genomic and the proteomic life science revolution, new 'omics' fields
are emerging. The metabolome encompasses the entity of small molecules—Most often end …