Aptamer‐functionalized field‐effect transistor biosensors for disease diagnosis and environmental monitoring

J Wang, D Chen, W Huang, N Yang, Q Yuan… - …, 2023 - Wiley Online Library
Nano‐biosensors that are composed of recognition molecules and nanomaterials have
been extensively utilized in disease diagnosis, health management, and environmental …

Label-free and reagent-less protein biosensing using aptamer-modified extended-gate field-effect transistors

T Goda, Y Miyahara - Biosensors and Bioelectronics, 2013 - Elsevier
We have developed biosensors based on an aptamer-modified field-effect transistor (FET)
for the detection of lysozyme and thrombin. An oligonucleotide aptamer as a sensitive and …

Predicting future prospects of aptamers in field-effect transistor biosensors

CA Vu, WY Chen - Molecules, 2020 - mdpi.com
Aptamers, in sensing technology, are famous for their role as receptors in versatile
applications due to their high specificity and selectivity to a wide range of targets including …

Synergizing nucleic acid aptamers with 1-dimensional nanostructures as label-free field-effect transistor biosensors

YL Khung, D Narducci - Biosensors and Bioelectronics, 2013 - Elsevier
Since the introduction by Gold et al. in 1990, nucleic acid aptamers had evolved to become
a true contender in biosensors for protein and cell detections. Aptamers are short strands of …

Detection and beyond: Challenges and advances in aptamer-based biosensors

H Yoo, H Jo, SS Oh - Materials Advances, 2020 - pubs.rsc.org
Beyond traditional needs of biosensors such as high sensitivity and selectivity for analyte
detection, newly emerging requirements including a real-time detection ability and in-field …

Recent advances in electrochemical aptasensors and genosensors for the detection of pathogens

R Nazari-Vanani, M Negahdary - Environmental Research, 2024 - Elsevier
In recent years, pathogenic microorganisms have caused significant mortality rates and
antibiotic resistance and triggered exorbitant healthcare costs. These pathogens often have …

Electrical detection of cancer biomarker using aptamers with nanogap break-junctions

A Ilyas, W Asghar, PB Allen, H Duhon… - …, 2012 - iopscience.iop.org
Epidermal growth factor receptor (EGFR) is a cell surface protein overexpressed in
cancerous cells. It is known to be the most common oncogene. EGFR concentration also …

Aptamer-engineered extended-gate field-effect transistor device for point-of-care therapeutic drug monitoring

M Zhang, J He, Y Zheng, G Shi, M Zhang - Analyst, 2022 - pubs.rsc.org
Herein, we report a portable point-of-care testing (POCT) device based on an aptamer-
engineered extended-gate field-effect transistor (EG-FET) for therapeutic monitoring of the …

Aptamer-based biosensors for environmental monitoring

EM McConnell, J Nguyen, Y Li - Frontiers in chemistry, 2020 - frontiersin.org
Due to their relative synthetic and chemical simplicity compared to antibodies, aptamers
afford enhanced stability and functionality for the detection of environmental contaminants …

Recent advances in electrochemical nanomaterial-based aptasensors for the detection of cancer biomarkers

M Negahdary, L Angnes - Talanta, 2023 - Elsevier
New technologies have provided suitable tools for rapid diagnosis of cancer which can
reduce treatment costs and even increase patients' survival rates. Recently, the …