Advances in human genetics are improving the understanding of a variety of inherited
cardiovascular diseases, including cardiomyopathies, arrhythmic disorders, vascular …

Importance Genetic testing is a valuable tool for managing inherited cardiovascular disease
in patients and families, including hypertrophic, dilated, and arrhythmogenic …

Genetic diseases that affect the cardiovascular system are relatively common and include
cardiac channelopathies, cardiomyopathies, aortopathies, hypercholesterolemias, and …

Cardiovascular genetics is a rapidly evolving subspecialty within cardiovascular medicine,
and its growth is attributed to advances in genome sequencing and genetic testing and the …

Although the power of family history to identify a genetic predisposition to disease has been
appreciated for some time, it is only recently, through the development of efficient methods …

Inherited cardiac diseases comprise a wide and heterogeneous spectrum of diseases of the
heart, including the cardiomyopathies and the arrhythmic diseases in structurally normal …

In the 15 years following the release of the first complete human genome sequences, our
understanding of rare and common genetic variation as determinants of cardiovascular …

Clinical genetic testing is now available for many cardio-vascular diseases, including
hypertrophic cardiomyopathy (HCM), familial dilated cardiomyopathy, and arrhythmogenic …

The recent completion of the Human Genome Project has provided an unprecedented
opportunity for researchers to identify high-risk patients and improve human health through …

Purpose The purpose of this document is to provide updated guidance for the genetic
evaluation of cardiomyopathy and for an approach to manage secondary findings from …