EM Bradbury - Trends in Biochemical Sciences, 1976 - cell.com
Many studies have led to the proposal of a subunit structure for chromatin similar to a string of beads. Each bead is thought to contain 200 base pairs of DNA coiled on the outside of a …
HJ Li - Nucleic acids research, 1975 - academic.oup.com
A model for chromatin structure is presented.(a) Each of four histone species, H2A (IIb1 or f2a2), H2B (IIb2 or f2b), H3 (III or f3) and H4 (IV or f2a1) can form a parallel dimer.(b) These …
S Bram, S Kouprach, P Baudy - Cold Spring Harbor Symposia …, 1978 - symposium.cshlp.org
A variety of studies (see, eg, this volume) have shown that chromatin consists of nuclease- resistant subunits (nucleosomes). Electron micrographs of chromatin, formaldehyde-fixed …
Chromatin fragments, prepared by brief digestion with DNase II or micrococcal nuclease, separated into a family of bands on sucrose gradients. The slowest migrating band with an S …
AJ Varshavsky, GP Georgiev - Molecular biology reports, 1975 - Springer
A new model for the fine structure of the chromatin subunit (or 'nucleosome') is proposed. The model is based on previous experimental findings 1–14 and on two new suggestions …
Abstract Earlier findings/1–10/bearing on a subunit organization of chromatin were confirmed and in some points detailed. Besides this, a large-scale isolation of chromatin …
The chromatin core particle consists of 140 base pairs of DNA wrapped around [1, 2] an oct 'americ histone core [3]. It has long been known from circular dichroism studies [4-71 that the …
HJ Li - International Journal of Biochemistry, 1976 - Elsevier
Chromatin and its major proteins, histones, have been investigated in the last decade by many scientists including biologists, biochemists, and biophysicists. Extensive reviews on …
M Noll - Nucleic acids research, 1974 - academic.oup.com
The digestion of chromatin in situ with DNase I reveals, after denaturation, a regular series of single stranded DNA fragments the lengths of which represent multiples of 10 bases. These …