Protective effects of quercetin and quercetin-5', 8-disulfonate against carbon tetrachloride-caused oxidative liver injury in mice

Y Cui, Y Han, X Yang, Y Sun, Y Zhao - Molecules, 2013 - mdpi.com
Oxidative stress is one of the major factors in the pathogenesis of liver disease. Quercetin is
a plant-based antioxidant traditionally used as a treatment for hepatic injury, but its poor …

[HTML][HTML] Therapeutic detoxification of quercetin against carbon tetrachloride-induced acute liver injury in mice and its mechanism

J Zhang, L Shi, X Xu, S Huang, B Lu, L Ji… - Journal of Zhejiang …, 2014 - ncbi.nlm.nih.gov
This study observes the therapeutic detoxification of quercetin, a well-known flavonoid,
against carbon tetrachloride (CCl 4) induced acute liver injury in vivo and explores its …

Quercetin treatment ameliorates systemic oxidative stress in cirrhotic rats

EK Vieira, S Bona, FC Di Naso… - International …, 2011 - Wiley Online Library
Our aim was to investigate whether the antioxidant quercetin protects against liver injury and
ameliorates the systemic oxidative stress in rats with common bile duct ligation. Secondary …

Quercetin protects mouse liver against CCl4-induced inflammation by the TLR2/4 and MAPK/NF-κB pathway

JQ Ma, Z Li, WR Xie, CM Liu, SS Liu - International immunopharmacology, 2015 - Elsevier
Quercetin (QE), a natural flavonoid, has many medical beneficial effects. However, its
protective effects against carbon tetrachloride (CCl 4) induced injury in liver have not been …

Quercetin metabolites and protection against peroxynitrite-induced oxidative hepatic injury in rats

A Yokoyama, A Yokoyama, H Sakakibara… - Free radical …, 2009 - Taylor & Francis
Quercetin has strong antioxidant potency. Quercetin-3′-O-sulphate (Q3′ S) and quercetin-
3-O-glucuronide (Q3GA) are the main circulating metabolites after consumption of quercetin …

The involvement of sirtuin 1 and heme oxygenase 1 in the hepatoprotective effects of quercetin against carbon tetrachloride-induced sub-chronic liver toxicity in rats

MK Kemelo, A Pierzynová, NK Canová… - Chemico-Biological …, 2017 - Elsevier
The present study was designed to evaluate the therapeutic potential of quercetin in a sub-
chronic model of hepatotoxicity. The roles of putative antioxidant enzymes, sirtuin 1 (SIRT1) …

Hepatoprotective Effects of 2′,4′-Dihydroxy-6′-methoxy-3′,5′-dimethylchalcone on CCl4-Induced Acute Liver Injury in Mice

WG Yu, J Qian, YH Lu - Journal of agricultural and food chemistry, 2011 - ACS Publications
In this paper, the hepatoprotective effects of 2′, 4′-dihydroxy-6′-methoxy-3′, 5′-
dimethylchalcone (DMC) on CCl4-induced acute liver injury in Kunming mice were …

Hepatoprotective effect of quercetin: From chemistry to medicine

S Miltonprabu, M Tomczyk, K Skalicka-Woźniak… - Food and Chemical …, 2017 - Elsevier
Liver diseases caused by viral hepatitis infections have a negative impact on global health.
Approximately 30 million people in the USA and 29 million people in the European Union …

Differential hepatoprotective mechanisms of rutin and quercetin in CCl4-intoxicated BALB/cN mice

R Domitrović, H Jakovac, V Vasiljev Marchesi… - Acta Pharmacologica …, 2012 - nature.com
Aim: To investigate the mechanisms underlying the protective effects of quercetin-rutinoside
(rutin) and its aglycone quercetin against CCl 4-induced liver damage in mice. Methods …

Protective effect of dietary flavonoid quercetin against lipemic-oxidative hepatic injury in hypercholesterolemic rats

AD Mariee, GM Abd-Allah… - Pharmaceutical …, 2012 - Taylor & Francis
Context: Quercetin, a dietary-derived flavonoid, is ubiquitous in fruits and vegetables and
plays important roles in human health by virtue of its antioxidant activity. Objective: This …