Acupuncture combined with curcumin attenuates carbon tetrachloride-induced hepatic fibrosis in rats

F Zhang, J Ma, Y Lu, GX Ni, CY Ni… - Acupuncture in …, 2012 - journals.sagepub.com
Background Increasingly, studies demonstrate the effectiveness of acupuncture therapy
against liver fibrosis. Curcumin is a natural product with antifibrotic effects, but has poor …

Acupuncture combined with curcumin disrupts platelet-derived growth factor β receptor/extracellular signal-regulated kinase signalling and stimulates extracellular …

XP Zhang, F Zhang, ZL Zhang, J Ma… - Acupuncture in …, 2012 - journals.sagepub.com
Background Acupuncture treatment has been increasingly used to treat chronic liver
diseases. We previously reported that acupuncture combined with curcumin, a natural …

Inhibition by curcumin of multiple sites of the transforming growth factor-beta1 signalling pathway ameliorates the progression of liver fibrosis induced by carbon …

Q Yao, B Xu, J Wang, H Liu, S Zhang, C Tu - BMC complementary and …, 2012 - Springer
Background At present there is no effective and accepted therapy for hepatic fibrosis.
Transforming growth factor (TGF)-β1 signaling pathway contributes greatly to hepatic …

[PDF][PDF] Antioxidant and anti-inflammatory effects of curcumin on CCl4–induced liver fibrosis in rats

NF Khedr, EG Khedr - Am. J. Biomed. Sci, 2014 - nwpii.com
Background: Liver fibrogenesis can lead to the development of cirrhosis and hepatocellular
carcinoma. This study was designed to evaluate the hepatoprotective effect of curcumin on …

Protective effects of curcumin against hepatic fibrosis induced by carbon tetrachloride: modulation of high-mobility group box 1, Toll-like receptor 4 and 2 expression

C Tu, Q Yao, B Xu, J Wang, C Zhou, S Zhang - Food and chemical …, 2012 - Elsevier
The aim of the study was to investigate the effect of curcumin on the liver fibrosis induced by
carbon tetrachloride (CCl4) in rats, and to elucidate its underlying molecular mechanisms …

Curcumin prevents liver fibrosis by inducing apoptosis and suppressing activation of hepatic stellate cells

JC Shu, YJ He, X Lv, GR Ye, LX Wang - Journal of natural medicines, 2009 - Springer
This study was designed to investigate the prophylactic effects and the mechanisms of
curcumin on liver fibrosis in rats. Liver fibrosis was induced in 72 Sprague Dawley rats by …

The synergistic hepatoprotective effect of curcumin and ginger against carbon tetrachloride induced-liver fibrosis in rats.

MK Ezz, GM Hamdy, RMA El-Atti - 2011 - cabidigitallibrary.org
The present study aimed to assess the hepatocellular protective activity of the co-
administration of curcumin fortified by ginger against carbon tetrachloride (CCl4)-induced …

The intervention of curcumin on rodent models of hepatic fibrosis: A systematic review and meta-analysis

YH Chu, BY Pang, M Yang, Q Meng, Y Leng - Plos one, 2024 - journals.plos.org
Objective This study aimed to evaluate the intervention effect of curcumin on hepatic fibrosis
in rodent models through systematic review and meta-analysis, in order to provide …

[HTML][HTML] Curcumin protects against liver fibrosis by attenuating infiltration of Gr1hi monocytes through inhibition of monocyte chemoattractant protein-1

R Huang, Y Liu, Y Xiong, H Wu, G Wang… - Discovery …, 2016 - discoverymedicine.com
Background & Aims. Liver fibrosis is concomitant with monocyte infiltration, which has been
highlighted as novel therapeutic targets for chronic liver diseases. We aimed to investigate …

Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes

ME Wang, YC Chen, IS Chen, SC Hsieh… - The Journal of nutritional …, 2012 - Elsevier
Inflammation and hepatic stellate cell (HSC) activation are the most crucial steps in the
formation of hepatic fibrosis. Hepatocytes damaged by viral or bacterial infection, alcohol or …