Pro-inflammatory effects of metals in persons and animals exposed to tobacco smoke

H Milnerowicz, M Ściskalska, M Dul - … of Trace Elements in Medicine and …, 2015 - Elsevier
Metals present in tobacco smoke have the ability to cause a pro-oxidant/antioxidant
imbalance through the direct generation of free radicals in accordance with the Fenton or …

Toxic elements in tobacco and in cigarette smoke: inflammation and sensitization

RS Pappas - Metallomics, 2011 - academic.oup.com
Biochemically and pathologically, there is strong evidence for both atopic and nonatopic
airway sensitization, hyperresponsiveness, and inflammation as a consequence of exposure …

An NF-κB–independent and Erk1/2-dependent mechanism controls CXCL8/IL-8 responses of airway epithelial cells to cadmium

E Cormet-Boyaka, K Jolivette… - Toxicological …, 2012 - academic.oup.com
Airway epithelial cells in the lung are the first line of defense against pathogens and
environmental pollutants. Inhalation of the environmental pollutant cadmium has been …

Cadmium induces lung inflammation independent of lung cell proliferation: a molecular approach

S Kundu, S Sengupta, S Chatterjee, S Mitra… - Journal of …, 2009 - Springer
Background Cadmium is one of the inflammation-related xenobiotics and has been
regarded as a potent carcinogen. The relationship between inflammation and cell …

Cadmium exposure to murine macrophages decreases their inflammatory responses and increases their oxidative stress

Y Jin, L Liu, S Zhang, R He, Y Wu, G Chen, Z Fu - Chemosphere, 2016 - Elsevier
Cadmium (Cd) is an environmental contaminant that poses serious risks to human and
wildlife health. The oxidative stress and inflammatory responses induced by Cd were …

Potential mechanisms of some selected heavy metals in the induction of inflammation and autoimmunity

AU Anka, AB Usman, AN Kaoje… - European Journal …, 2022 - journals.sagepub.com
Inflammation is a physiological event that protects tissues from infection and injury. Chronic
inflammation causes immune cell over activation and sustained release of inflammatory …

Dietary zinc mediates inflammation and protects against wasting and metabolic derangement caused by sustained cigarette smoke exposure in mice

CJ Lang, M Hansen, E Roscioli, J Jones, C Murgia… - Biometals, 2011 - Springer
In mouse asthma models, inflammation can be modulated by zinc (Zn). Given that appetite
loss, muscle wasting and poor nutrition are features of chronic obstructive pulmonary …

Metals in cigarette smoke

D Bernhard, A Rossmann, G Wick - IUBMB life, 2005 - Wiley Online Library
Metals are vital for a huge number of physiological processes in the human body, but can
also destroy health when the concentration is not within the physiologically favourable …

The dysregulation of inflammatory pathways triggered by copper exposure

H Deng, S Zhu, H Yang, H Cui, H Guo, J Deng… - Biological trace element …, 2023 - Springer
Copper (Cu) is an essential micronutrient for both human and animals. However, excessive
intake of copper will cause damage to organs and cells. Inflammation is a biological …

Differential ability of transition metals to induce pulmonary inflammation

TM Rice, RW Clarke, JJ Godleski, E Al-Mutairi… - Toxicology and Applied …, 2001 - Elsevier
Transition metals are components of airborne particles and have been implicated in adverse
health effects. The relative inflammatory potential of these metals is usually inferred from …