Introduction Several months into the COVID-19 pandemic, safe and effective treatments
against this global health disaster have yet to be identified. Clinical research trials around …

There is an urgent need for drugs, therapies and vaccines to be available to protect the
human population against COVID-19. One of the first approaches taken in the COVID-19 …

There are currently no proven or approved treatments for coronavirus disease 2019 (COVID‐
19). Early anecdotal reports and limited in vitro data led to the significant uptake of …

The efficacy and safety of hydroxychloroquine (HCQ) for the prevention and treatment of
COVID-19 has received great attention, and most notably, the enthusiasm for HCQ has been …

To the editor, Since December 2019, a pandemic outbreak of emerging coronavirus disease
(COVID-19) due to SARS-CoV-2 is spreading, resulting in exponentially increasing numbers …

Chloroquine and hydroxychloroquine are drugs that have shown in vitro activity on the
replication of certain coronaviruses. In the context of the SARS-Cov-2 epidemic, the virus …

Introduction Over the last few months, coronavirus disease 2019 (COVID-19) pandemic
caused by the novel coronavirus SARS-CoV-2 has posed a serious threat to public health …

PETAL Clinical Trials Network, focused on hospitalized patients with moderate to severe
disease. In this wellconducted, appropriately powered clinical trial, the authors randomized …

The COVID-19 pandemic has required clinicians to urgently identify new treatment options
or the re-purposing of existing drugs. Of particular interest are chloroquine (CQ) and …

The impact of the COVID-19 pandemic worldwide has led to a desperate search for effective
drugs and vaccines. There are still no approved agents for disease prophylaxis. We thus …