Abstract Effects of extracellular applications of different types of Ca 2+ channel blocking
agents (Mn 2+, verapamil, and nisoldipine) on action-potential duration and membrane …

The voltage dependence and the kinetics of block by verapamil of L-type calcium current (I
Ca) were investigated in ventricular myocytes from rat hearts using the whole-cell patch …

The phosphodiesterase inhibitors 3-isobutyl-1-methylxanthine (IBMX; 100 microM) and
papaverine (100 microM) increased peak L-type Ca current (ICa) more than fivefold in a way …

The effect of 20 mmextracellularly applied 2, 3-Butanedione monoxime (BDM) onl-type
Ca2+ channel charge movement current was studied in whole-cell voltage-clamped guinea …

抄録 Effects of K+ channel modulators, cromakalim and E4031 [1-[2-(6-methyl-2-pyridyl)-
ethyl]-4-(4-methylsulfonylaminobenzoyl) piperidine], on the relationship between the action …

First-generation Ca2+ channel antagonists depress myocardial contractility, but many of the
newer Ca2+ channel blockers have a high degree of “vascular selectivity”. This study …

It has been shown that the occurrence of the transient inward current, which is responsible
for triggered activity, was often associated with propagating regions of increased …

Diltiazem is a benzothiazepine Ca2+ channel blocker used clinically for its antihypertensive
and antiarrhythmic effects. We studied the mechanism of diltiazem blockade by recording L …

The electrophysiological effects of MPC-1304, a novel calcium antagonist, were examined
using the conventional microelectrode and whole-cell patch-clamp techniques in guinea-pig …

The effects of the phenylalkylamines verapamil, gallopamil, and devapamil on L-type
calcium currents (I Ca) were studied in ventricular myocytes from rat hearts using the whole …