Melatonin (Mel) has neuroprotective effects; however, its roles in hypoxic-ischemic brain
damage (HIBD) and the underlying mechanisms remain unknown. We aimed to explore its …

Oxidative stress and energy imbalance strongly correlate in neurodegenerative diseases.
Repeated concussion is becoming a serious public health issue with uncontrollable adverse …

Chronic cerebral hypoperfusion (CCH) is the most common cause of cognitive impairment,
which is commonly found in Alzheimer's disease (AD) and vascular dementia (VaD) …

Melatonin has demonstrated a potential protective effect in central nervous system. Thus, it
is interesting to determine whether pre‐ischemia melatonin administration could protect …

Intracerebral hemorrhage (ICH) is a cerebrovascular disease with high mortality and
morbidity, and the effective treatment is still lacking. We designed this study to investigate …

Traumatic brain injury (TBI) is a principal cause of death and disability worldwide. Melatonin,
a hormone made by the pineal gland, is known to have anti-inflammatory and antioxidant …

Ischemic stroke is a leading cause of mortality and morbidity worldwide, with
neuroinflammation playing a key role in its pathophysiology. Microglia, the primary immune …

Melatonin has many protective effects against ischemic stroke, but the underlying
neuroprotective mechanisms are not fully understood. Our aim was to explore the …

Melatonin, a natural product of the pineal gland, has been shown to protect against ischemic
stroke, but the molecular mechanisms underlying its protective function are not fully …

Although traumatic brain injury (TBI) is a common cause of death and disability worldwide,
there is currently a lack of effective therapeutic drugs and targets. To reveal the complex …