Heterotrimeric G protein–coupled receptors (GPCRs) are found on the surface of all cells of multicellular organisms and are major mediators of intercellular communication. More than …
Y Hattori, MC Michel - Frontiers in Pharmacology, 2020 - frontiersin.org
G protein-coupled receptors (GPCRs) are the largest family of plasma membrane proteins mediating cellular responses to a wide variety of external stimuli and can be crucially …
The relevance of the family of G protein-coupled receptor kinases (GRKs) is based on its key participation in the regulation and intracellular dynamics of the largest family of membrane …
G protein-mediated signal transduction by seven transmembrane G protein-coupled receptors (GPRs) is one of the most prevalent signaling systems in the body. Rapid agonist …
H Kurose - Biomolecules & Therapeutics, 2011 - koreascience.kr
G protein-coupled receptor kinases (GRKs) and ${\beta} $-arrestins have been known as regulators of G protein-coupled receptors. However, it has been recently reported that GRKs …
R Zhai, J Snyder, S Montgomery, PY Sato - Cellular signalling, 2022 - Elsevier
G-protein coupled receptor (GPCR) kinases (GRKs) and β-arrestins play key roles in GPCR and non-GPCR cellular responses. In fact, GRKs and arrestins are involved in a plethora of …
Agonist activation of G protein-coupled receptors promotes sequential interaction of the receptor with heterotrimeric G proteins, G protein-coupled receptor kinases (GRKs), and …
Agonist activation of G protein-coupled receptors promotes sequential interaction of the receptor with heterotrimeric G proteins, G protein-coupled receptor kinases (GRKs), and …
SSG Ferguson, LS Barak, J Zhang… - Canadian journal of …, 1996 - cdnsciencepub.com
G-protein-coupled receptors (GPCRs) represent a large family of proteins that transduce extracellular signals to the interior of cells. Signalling through these receptors rapidly …