Role of G-protein-coupled receptor kinases in cell migration and signal transduction

X Cai, J Chen, J Zhang, B Bai - Chinese Journal of …, 2011 - pesquisa.bvsalud.org
ABSTRACT G-protein-coupled receptor kinases (GRKs) are a family of serine/threonine
protein kinases. The investigators pay much attention to the roles of GRKs in the signal …

Physiological roles of G protein–coupled receptor kinases and arrestins

RT Premont, RR Gainetdinov - Annu. Rev. Physiol., 2007 - annualreviews.org
Heterotrimeric G protein–coupled receptors (GPCRs) are found on the surface of all cells of
multicellular organisms and are major mediators of intercellular communication. More than …

G protein-coupled receptor kinases (GRKS) and β-arrestins: New insights into disease regulators

Y Hattori, MC Michel - Frontiers in Pharmacology, 2020 - frontiersin.org
G protein-coupled receptors (GPCRs) are the largest family of plasma membrane proteins
mediating cellular responses to a wide variety of external stimuli and can be crucially …

G Protein-Coupled Receptor Kinases Take Central Stage

F Mayor Jr, C Murga - Cells, 2022 - mdpi.com
The relevance of the family of G protein-coupled receptor kinases (GRKs) is based on its key
participation in the regulation and intracellular dynamics of the largest family of membrane …

[图书][B] Molecular mechanisms of regulation of G protein-coupled receptor signaling by arrestins

JG Krupnick - 1999 - search.proquest.com
G protein-mediated signal transduction by seven transmembrane G protein-coupled
receptors (GPRs) is one of the most prevalent signaling systems in the body. Rapid agonist …

Atypical actions of G protein-coupled receptor kinases

H Kurose - Biomolecules & Therapeutics, 2011 - koreascience.kr
G protein-coupled receptor kinases (GRKs) and ${\beta} $-arrestins have been known as
regulators of G protein-coupled receptors. However, it has been recently reported that GRKs …

Double life: How GRK2 and β-arrestin signaling participate in diseases

R Zhai, J Snyder, S Montgomery, PY Sato - Cellular signalling, 2022 - Elsevier
G-protein coupled receptor (GPCR) kinases (GRKs) and β-arrestins play key roles in GPCR
and non-GPCR cellular responses. In fact, GRKs and arrestins are involved in a plethora of …

[PDF][PDF] Historical Perspective of the G Protein-Coupled Receptor Kinase Family. Cells 2021, 10, 555

JL Benovic - 2021 - jdc.jefferson.edu
Agonist activation of G protein-coupled receptors promotes sequential interaction of the
receptor with heterotrimeric G proteins, G protein-coupled receptor kinases (GRKs), and …

Historical perspective of the G protein-coupled receptor kinase family

JL Benovic - Cells, 2021 - mdpi.com
Agonist activation of G protein-coupled receptors promotes sequential interaction of the
receptor with heterotrimeric G proteins, G protein-coupled receptor kinases (GRKs), and …

G-protein-coupled receptor regulation: role of G-protein-coupled receptor kinases and arrestins

SSG Ferguson, LS Barak, J Zhang… - Canadian journal of …, 1996 - cdnsciencepub.com
G-protein-coupled receptors (GPCRs) represent a large family of proteins that transduce
extracellular signals to the interior of cells. Signalling through these receptors rapidly …