[HTML][HTML] An in silico hybrid continuum-/agent-based procedure to modelling cancer development: Interrogating the interplay amongst glioma invasion, vascularity and …
This paper develops a three-dimensional in silico hybrid model of cancer, which describes
the multi-variate phenotypic behaviour of tumour and host cells. The model encompasses …
the multi-variate phenotypic behaviour of tumour and host cells. The model encompasses …
[HTML][HTML] Knowledge-based computational models
W Verhaegh, A Van de Stolpe - Oncotarget, 2014 - ncbi.nlm.nih.gov
In our recent paper [1], we describe a biologydriven approach to translate cancer genomic
data into clinically actionable information for personalized patient therapy selection. Despite …
data into clinically actionable information for personalized patient therapy selection. Despite …
[HTML][HTML] Simulating brain tumor heterogeneity with a multiscale agent-based model: linking molecular signatures, phenotypes and expansion rate
We have extended our previously developed 3D multi-scale agent-based brain tumor model
to simulate cancer heterogeneity and to analyze its impact across the scales of interest …
to simulate cancer heterogeneity and to analyze its impact across the scales of interest …
Simulating cancer growth with multiscale agent-based modeling
There have been many techniques developed in recent years to in silico model a variety of
cancer behaviors. Agent-based modeling is a specific discrete-based hybrid modeling …
cancer behaviors. Agent-based modeling is a specific discrete-based hybrid modeling …
[HTML][HTML] Are all models wrong?
H Enderling, O Wolkenhauer - Computational and systems …, 2020 - ncbi.nlm.nih.gov
Mathematical modeling in cancer is enjoying a rapid expansion (Brady & Enderling, 2019).
For collegial discussion across disciplines, many-if not all of us-have used the aphorism that …
For collegial discussion across disciplines, many-if not all of us-have used the aphorism that …