The nucleosome is the ubiquitous and fundamental DNA-protein complex of the eukaryotic
chromosome, participating in the packaging of DNA and in the regulation of gene …

We have characterized the structure of transcriptionally active nucleosome subunits using
electron spectroscopic imaging. Individual nucleosomes were analyzed in terms of total …

The structure of the nucleosome core particle, the basic repeating unit in eukaryotic
chromatin, allows us to view the role of histones in regulating transcription, and in …

This chapter contains sections titled: Introduction Experimental Systems Nucleosome–
Nucleosome Interactions DNA Interactions with the Histone Octamer Protein Core …

Chromatin: The nucleosome unwrapped: Current Biology Skip to Main Content Advertisement
Current Biology This journal offers authors two options (open access or subscription) to publish …

In this study, electron tomograms of plunge-frozen isolated chromatin in both open and
compacted form were recorded. We have resolved individual nucleosomes in these …

The high resolution structure of the nucleosome core particle of chromatin reveals the form
of DNA that is predominant in living cells and offers a wealth of information on DNA binding …

* Present address: Department of Biochemistry and Biophysics, University of California at
San Francisco, San Francisco, California 94143. to function in regulation by closing or …

We have recently reported that certain core histone-DNA contacts are altered in
nucleosomes during chromatin unfolding (Usachenko, SI, Gavin IM, and Bavykin, SG (1996) …

Genetic studies have identified residues in the structured regions of the histones that are
critically involved in the formation of heterochromatin. Any investigation of the events that …