Examining disease severity and symptom improvement with patient and physician assessments: Results from a phase iv analysis of apremilast in patients with …

MG Lebwohl, JM Jackson, J Bagel, E Levi… - 2018 - scholarlycommons.henryford.com
Background: UNVEIL is the first study of apremilast in patients (pts) with moderate psoriasis
(body surface area [BSA] 5%-10%) naive to biologic and systemic therapy. Physician and pt …

Efficacy and safety of apremilast in patients with moderate plaque psoriasis (UNVEIL phase 4 study)

B Strober, J Bagel, JM Lebwohl, L Stein Gold… - 2017 - scholarlycommons.henryford.com
Abstract Introduction and Objectives: Patients (pts) with moderate plaque psoriasis are often
inadequately treated (Armstrong, 2013), and there remains an unmet medical need for an …

Efficacy and safety of apremilast in patients with moderate plaque psoriasis with lower BSA: week 16 results from the UNVEIL study

B Strober, J Bagel, M Lebwohl… - Journal of drugs in …, 2017 - pubmed.ncbi.nlm.nih.gov
INTRODUCTION: Many options are available for patients with moderate to severe plaque
psoriasis. Patients with moderate disease, however, are often undertreated and do not …

Efficacy and Safety of Apremilast in Systemic-and Biologic-Naive Patients With Moderate Plaque Psoriasis: 52-Week Results of UNVEIL.

J Bagel, M Lebwohl, JM Jackson, R Chen… - Journal of drugs in …, 2018 - europepmc.org
BACKGROUND: Many patients with moderate plaque psoriasis are undertreated despite
broadening treatment options. In the phase IV UNVEIL study, oral apremilast demonstrated …

[HTML][HTML] Apremilast mechanism of efficacy in systemic-naive patients with moderate plaque psoriasis: pharmacodynamic results from the UNVEIL study

B Strober, A Alikhan, B Lockshin, R Shi, J Cirulli… - Journal of …, 2019 - Elsevier
Background Pharmacodynamic (PD) subanalyses of clinical trials in patients with moderate
to severe psoriasis demonstrated the efficacy of apremilast correlated with reductions in …

Real-World Clinical Experience With Apremilast in a Large US Retrospective Cohort Study of Patients With Moderate to Severe Plaque Psoriasis.

A Armstrong, E Levi - Journal of Drugs in Dermatology: JDD, 2017 - europepmc.org
OBJECTIVE: To examine real-world use and patient outcomes with apremilast, an oral
PDE4 inhibitor, in the dermatology practice set-ting for treatment of patients with moderate to …

Long‐term efficacy and safety of apremilast in the treatment of plaques psoriasis: A real‐world, single‐center experience

G Radi, A Campanati, F Diotallevi… - Dermatologic …, 2021 - Wiley Online Library
Apremilast is a small molecule approved for the treatment of plaques psoriasis and adult
psoriatic arthritis. Pivotal studies have demonstrated short and long term efficacy and safety …

Efficacy and safety of apremilast in patients with mild-to-moderate plaque psoriasis: Results of a phase 3, multicenter, randomized, double-blind, placebo-controlled …

LS Gold, K Papp, D Pariser, L Green, N Bhatia… - Journal of the American …, 2022 - Elsevier
Background Patients with mild-to-moderate psoriasis may have substantial quality-of-life
impairment. Objective To evaluate apremilast 30 mg twice daily for mild-to-moderate …

Apremilast treatment of plaque psoriasis (PsO) after systemic therapy in Spanish clinical practice: Data from the APPROPRIATE study

P de la Cueva, S Armesto, E Montesinos… - JEADV Clinical …, 2023 - Wiley Online Library
Background Despite the proven efficacy and safety of apremilast to treat plaque psoriasis
(PsO), data regarding its real‐world use and patient‐perceived benefits are limited …

33354 Efficacy of apremilast in patients with mild to moderate psoriasis assessed by the physician global assessment and body surface area composite tool: Post hoc …

LF Stein Gold, K Papp, D Pariser, H Sofen… - 2022 - scholarlycommons.henryford.com
Background: In ADVANCE (NCT03721172), apremilast 30 mg BID (APR) demonstrated
significantly greater sPGA response vs. PBO at Week 16 (22% vs. 4%; P<. 0001) in patients …