The aim of the study was to investigate the effect of curcumin on the liver fibrosis induced by
carbon tetrachloride (CCl4) in rats, and to elucidate its underlying molecular mechanisms …

Background At present there is no effective and accepted therapy for hepatic fibrosis.
Transforming growth factor (TGF)-β1 signaling pathway contributes greatly to hepatic …

This study aimed to investigate the protective effect of curcumin against carbon tetrachloride
(CCl4)-induced acute liver injury in a mouse model, and to explain the underlying …

Background: Liver fibrogenesis can lead to the development of cirrhosis and hepatocellular
carcinoma. This study was designed to evaluate the hepatoprotective effect of curcumin on …

Background & Aims. Liver fibrosis is concomitant with monocyte infiltration, which has been
highlighted as novel therapeutic targets for chronic liver diseases. We aimed to investigate …

Objective Epithelial mesenchymal transition (EMT) and inflammation have been identified as
carcinogenic agents. This study aims to investigate whether inhibition of trichloroethylene …

Curcumin, an anti-inflammatory and antioxidant compound, was evaluated for its ability to
suppress acute carbon tetrachloride-induced liver damage. Acute hepatotoxicity was …

Cirrhosis is a chronic liver disease. The present work aimed to evaluate the regulatory
immune effect of curcumin in hepatic cirrhosis induced by carbon tetrachloride (CCl4) …

Abstract Introduction and Objectives Curcumin, a polyphenol, is a natural compound that
has been widely studied as a hepatoprotector; however, only a few studies have examined …

Inflammation and hepatic stellate cell (HSC) activation are the most crucial steps in the
formation of hepatic fibrosis. Hepatocytes damaged by viral or bacterial infection, alcohol or …