Abstract Background and Objectives Antihypertensive therapy is effective in reducing the
risk of major adverse cardiovascular events. However, blood pressure (BP) control rate …

Objective To evaluate the effects of amlodipine-based antihypertensive combination
regimen on blood pressure control and impact on cardiovascular events. Methods From Oct …

Abstract The Chinese Hypertension Intervention Efficacy Study (CHIEF) is a multi-centre
randomized controlled clinical trial comparing the effects of amlodipine+ angiotensin II …

Objective: This study was designed to explore antihypertensive efficacy and safety of a
combination of amlodipine (CCB) and valsartan (ARB), in essential hypertensive patients …

Summary Background: Chinese Hypertension Intervention Efficacy (CHIEF) study is a large‐
scale randomised clinical trial across China, which compares the efficacy of two combination …

Objective: To evaluate the long-term tolerability and efficacy of the amlodipine/valsartan
5/320 mg once daily (od) combination in hypertensive patients. Methods: This was a 54 …

Objective: When hypertension is uncontrolled by routine treatment with an angiotensin II
receptor blocker (ARB) and the calcium channel blocker amlodipine (5 mg), the dose of …

Objectives. In this study, the effectiveness of amlodipine/valsartan single-pill combination
was assessed in hypertensive patients with diabetes, metabolic risk or overweight. Methods …

Aims: To demonstrate the benefit of the combination amlodipine/valsartan 5/160 mg over
amlodipine 10 mg, in producing a lower incidence of peripheral oedema for a comparable …

Achieving target blood pressure (BP) is influenced by baseline BP. Post hoc analyses of a
placebo-controlled trial of amlodipine/valsartan versus monotherapies were conducted to …