Bioanalytical techniques in nontargeted clinical lipidomics

T Hyötyläinen, M Orešič - Bioanalysis, 2016 - Taylor & Francis
Lipidomic analysis aims at comprehensive characterization of molecular lipids in biological
systems. Due to the central role of lipid metabolism in many devastating diseases, lipidomics …

[HTML][HTML] Recent advances towards mass spectrometry-based clinical lipidomics

S Salihovic, S Lamichane, T Hyötyläinen… - Current opinion in …, 2023 - Elsevier
The objective of this review is to provide a comprehensive summary of the latest
methodological advancements and emerging patterns in utilizing lipidomics in clinical …

New trends in lipidomics

M Holčapek - Analytical and Bioanalytical Chemistry, 2024 - Springer
Lipidomics encompasses the large-scale identification and quantification of diverse lipids
within biological systems, which play fundamental roles in the metabolism of humans …

Advances in sample preparation and analytical techniques for lipidomics study of clinical samples

CC Teo, WPK Chong, E Tan, NB Basri, ZJ Low… - TrAC Trends in …, 2015 - Elsevier
Lipids play multiple key roles in biological systems, including acting as secondary energy
reserves, being components of cellular membranes and participating in cell-signaling …

High throughput quantitative molecular lipidomics

HR Jung, T Sylvänne, KM Koistinen, K Tarasov… - … Et Biophysica Acta (BBA …, 2011 - Elsevier
Applications in biomedical research increasingly demand detailed lipid molecule
information acquired at high throughput. Although the recent advances in lipidomics offer to …

Chewing the fat: How lipidomics is changing our understanding of human health and disease in 2022

C Géhin, SJ Fowler, DK Trivedi - Analytical Science Advances, 2023 - Wiley Online Library
Lipids are biological molecules that play vital roles in all living organisms. They perform
many cellular functions, such as 1) forming cellular and subcellular membranes, 2) storing …

A beginner's guide to lipidomics

JV Swinnen, J Dehairs - The Biochemist, 2022 - portlandpress.com
Lipidomics refers to the large-scale analysis of the complete set of lipids–the 'lipidome'–in
any biological system. Methodologically, it heavily relies on mass spectrometry, an analytic …

Lipidomics: techniques, applications, and outcomes related to biomedical sciences

K Yang, X Han - Trends in biochemical sciences, 2016 - cell.com
Lipidomics is a newly emerged discipline that studies cellular lipids on a large scale based
on analytical chemistry principles and technological tools, particularly mass spectrometry …

Analytical strategies in lipidomics and applications in disease biomarker discovery

C Hu, R van der Heijden, M Wang… - … of Chromatography B, 2009 - Elsevier
Lipidomics is a lipid-targeted metabolomics approach aiming at comprehensive analysis of
lipids in biological systems. Recently, lipid profiling, or so-called lipidomics research, has …

Lipidomics, en route to accurate quantitation

SM Lam, H Tian, G Shui - Biochimica et Biophysica Acta (BBA)-Molecular …, 2017 - Elsevier
Accurate quantitation is prerequisite for the sustainable development of lipidomics via
enabling its applications in various biological and biomedical settings. In this review, the …