We evaluated the clinical and haematological features of 29 sickle cell anaemia patients
with associated alpha-thalassaemia and 22 sickle cell homozygotes with a normal alpha …

Background and objectives: The clinical manifestation in sickle cell disease (SCD) patients
varies from one individual to another due to factors like the presence of alpha-thalassaemia …

During an extensive investigation to determine the frequency of sickle cell and thalassaemia
genes in the Saudi population, 22 cases with S/β°-thalassaemia were identified and the …

Haematological values were determined in 246 sickle cell anaemia (SCA) patients in three
centres in Benin City, Nigeria, as well as 84 control subjects with haemoglobin A (HbAA) …

Background Sickle cell disease is a protean disease with limited data on Nigeria's
phenotypic and genetic variants. This study was conducted to provide baseline data on …

This study was conducted in the Eastern Province of Saudi Arabia where both thalassaemia
and Hb S genes occur at a high frequency. In 171 Saudi Hb S heterozygotes, the range for …

The influence of the α-thalassaemia gene on the haematological, biochemical and clinical
presentation of sickle cell anaemia (SC A) was investigated in Saudi patients with 1 or 2 α …

Background: Sickle cell disease (SCD) is a monogenic, phenotypically highly variable
disease with multisystem pathology. The phenotypic heterogeneity of SCD is attributed to …

Introduction Bahrain has high prevalence rates of sickle cell and thalassemia in the
population. This study reports the frequencies and phenotypic characteristics of α‐and/or β …

The sickle cell (HbS) gene occurs at a variable frequency in the Middle Eastern Arab
countries, with characteristic distribution patterns and representing an overall picture of …