Background & objectives Isolation of functional pancreatic islets for diabetes research and
clinical islet transplantation stands as a big challenge despite the advancements in the field …

Objective: Isolated pancreatic islets are valuable resources for a wide range of research,
including cell replacement studies and cell-based platforms for diabetes drug discovery and …

Objective Isolated pancreatic islets are valuable resources for a wide range of research,
including cell replacement studies and cell-based platforms for diabetes drug discovery and …

Islet transplantation represents a promising therapeutic approach for diabetes management,
yet the isolation and evaluation of pancreatic islets remain challenging. This study focuses …

Pancreatic islet isolation is critical for type 2 diabetes research. Although-omics approaches
have shed light on islet molecular profiles, inconsistencies persist; on the other hand …

Successful islet isolation is the key to islet transplantation in diabetic patients. However, islet
isolation is a technically complex and time-consuming manual process. Optimizing the islet …

Islets of Langerhans isolated from experimental animals, such as mice and rats, have
contributed much to our understanding of the mechanisms by which pancreatic β-cells …

This review highlights some recent developments and diversified applications of islets in
diabetes research as they are rapidly emerging as a model system in biomedical and …

Islets of Langerhans and β-cell isolation constitute routinely used cell models for diabetic
research, and refining islet isolation protocols and cell quality assessment is a high priority …

Islets of Langerhans are clusters of endocrine cells embedded within the exocrine pancreas.
Islets constitute only approximately 1–2% of the total pancreas mass in all species, so …