In vivo visualization using MRI T2 mapping of induced osteochondrosis and osteochondritis dissecans lesions in goats undergoing controlled exercise

F Tóth, FH David, E LaFond, L Wang… - Journal of …, 2017 - Wiley Online Library
In vivo visualization of subclinical osteochondrosis (OC) lesions, characterized by necrosis
of epiphyseal growth cartilage, is necessary to clarify the pathogenesis of this disease …

Multiparametric MRI of epiphyseal cartilage necrosis (osteochondrosis) with histological validation in a goat model

L Wang, MJ Nissi, F Tóth, J Shaver, CP Johnson… - PloS one, 2015 - journals.plos.org
Purpose To evaluate multiple MRI parameters in a surgical model of osteochondrosis (OC)
in goats. Methods Focal ischemic lesions of two different sizes were induced in the …

[HTML][HTML] Surgical induction, histological evaluation, and MRI identification of cartilage necrosis in the distal femur in goats to model early lesions of osteochondrosis

F Tóth, MJ Nissi, L Wang, JM Ellermann… - Osteoarthritis and …, 2015 - Elsevier
Objective Identify and interrupt the vascular supply to portions of the distal femoral articular-
epiphyseal cartilage complex (AECC) in goat kids to induce cartilage necrosis, characteristic …

An update on the pathogenesis of osteochondrosis

K Olstad, S Ekman, CS Carlson - Veterinary pathology, 2015 - journals.sagepub.com
Osteochondrosis is defined as a focal disturbance in endochondral ossification. The
cartilage superficial to an osteochondrosis lesion can fracture, giving rise to fragments in …

Quantitative susceptibility mapping detects abnormalities in cartilage canals in a goat model of preclinical osteochondritis dissecans

L Wang, MJ Nissi, F Toth, CP Johnson… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose To use quantitative susceptibility mapping (QSM) to investigate changes in
cartilage canals in the distal femur of juvenile goats after their surgical transection. Methods …

Micro-computed tomography of early lesions of osteochondrosis in the tarsus of foals

K Olstad, V Cnudde, B Masschaele, R Thomassen… - Bone, 2008 - Elsevier
INTRODUCTION: Osteochondrosis (OC) is an important developmental orthopedic disease
of human and equine patients. The disease is defined as a focal disturbance in enchondral …

Novel application of magnetic resonance imaging demonstrates characteristic differences in vasculature at predilection sites of osteochondritis dissecans

F Toth, MJ Nissi, JM Ellermann… - … American journal of …, 2015 - journals.sagepub.com
Background: Understanding the pathogenesis of osteochondrosis/osteochondritis dissecans
and other developmental orthopaedic diseases that are thought to occur secondary to …

Epiphyseal cartilage vascular architecture at the distal humeral osteochondritis dissecans predilection site in juvenile pigs

F Tóth, MJ Nissi, AR Armstrong… - Journal of …, 2024 - Wiley Online Library
Failure of endochondral ossification due to interruption of the vascular supply to the
epiphyseal cartilage is a critical step in the development of osteochondritis dissecans …

Ossification defects detected in CT scans represent early osteochondrosis in the distal femur of piglets

K Olstad, J Kongsro, E Grindflek… - Journal of Orthopaedic …, 2014 - Wiley Online Library
The purpose of the current study was to validate the use of CT for selection against
osteochondrosis in pigs by calculating positive predictive value and comparing it to the …

Differences in the vascular tree of the femoral trochlear growth cartilage at osteochondrosis‐susceptible sites in foals revealed by SWI 3T MRI

G Martel, S Kiss, G Gilbert… - Journal of …, 2016 - Wiley Online Library
Focal ischemic chondronecrosis of epiphyseal growth cartilage (EGC) during endochondral
ossification is believed to be a key early event on the pathway to osteochondrosis (OC) in …