Methotrexate-associated pneumonitis and rheumatoid arthritis-interstitial lung disease: current concepts for the diagnosis and treatment

GE Fragoulis, E Nikiphorou, J Larsen, P Korsten… - Frontiers in …, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a type of inflammatory arthritis that affects~ 1% of the general
population. Although arthritis is the cardinal symptom, many extra-articular manifestations …

Interstitial lung disease in patients with rheumatoid arthritis: spontaneous and drug induced

RW Hallowell, MR Horton - Drugs, 2014 - Springer
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease characterized by the
destruction of articular joint structures. RA is a systemic condition that often affects multiple …

Interstitial lung diseases induced or exacerbated by DMARDS and biologic agents in rheumatoid arthritis: a systematic literature review

C Roubille, B Haraoui - Seminars in arthritis and rheumatism, 2014 - Elsevier
Objective To review published cases of induced or exacerbated interstitial lung disease
(ILD) in rheumatoid arthritis (RA) associated with non-biologic disease-modifying …

Rheumatoid arthritis-related interstitial lung disease (RA-ILD): methotrexate and the severity of lung disease are associated to prognosis

J Rojas-Serrano, D Herrera-Bringas… - Clinical …, 2017 - Springer
Interstitial lung disease (ILD) is a severe rheumatoid arthritis (RA) manifestation. The worst
survival has been associated with usual interstitial pneumonia (UIP) definitive pattern in high …

Treatment of rheumatoid arthritis-associated interstitial lung disease: a perspective review

K Iqbal, C Kelly - Therapeutic advances in musculoskeletal …, 2015 - journals.sagepub.com
Rheumatoid arthritis (RA) is a systemic autoimmune disease affecting 0.5–1% of the
worldwide population. Whilst predominantly causing chronic pain and inflammation in …

Methotrexate and interstitial lung disease: controversies and questions. A narrative review of the literature

GE Fragoulis, R Conway, E Nikiphorou - Rheumatology, 2019 - academic.oup.com
MTX, which is the anchor-drug for the treatment of RA, has been associated with lung injury
and in particular with MTX-related pneumonitis (M-pneu). Although the frequency of M-pneu …

Methotrexate and rheumatoid arthritis associated interstitial lung disease

PA Juge, JS Lee, J Lau… - European …, 2021 - Eur Respiratory Soc
Question addressed by the study Methotrexate (MTX) is a key anchor drug for rheumatoid
arthritis (RA) management. Fibrotic interstitial lung disease (ILD) is a common complication …

The multifaceted aspects of interstitial lung disease in rheumatoid arthritis

L Cavagna, S Monti, V Grosso, N Boffini… - BioMed research …, 2013 - Wiley Online Library
Interstitial lung disease (ILD) is a relevant extra‐articular manifestation of rheumatoid
arthritis (RA) that may occur either in early stages or as a complication of long‐standing …

Does methotrexate cause progressive fibrotic interstitial lung disease? A systematic review

JK Dawson, E Quah, B Earnshaw, C Amoasii… - Rheumatology …, 2021 - Springer
The aim is to evaluate the published evidence on whether methotrexate (MTX) use causes
progressive fibrotic interstitial lung disease (fILD). This PRISMA-compliant systematic review …

Interstitial lung disease in rheumatoid arthritis: recent advances

DS Kim - Current opinion in pulmonary medicine, 2006 - journals.lww.com
Because the usual interstitial pneumonia pattern may be more frequent in rheumatoid
arthritis and some data suggest a poor prognosis for rheumatoid arthritis-associated …