Spermatogenesis is the complex process whereby relatively undifferentiated germinal cells
undergo biochemical and morphological modifications to form spermatozoa. Sertoli cells are …

The" nurse cell" concept developed as a result of the morphological relationships between
germ cells and Sertoli cells, and because of the junctional barrier defined by Sertoli cells …

During the last few years, there has been an upsurge of information on factors that stimulate
and regulate Sertoli cell function. It is now known that cultured Sertoli cells can respond to …

Publisher Summary The close morphological relationship between Sertoli cells and the
developing germ cells offers the Sertoli cell a unique position within the testis; however, to …

During the past decade the attention of many investigators has been directed to the role of
the Sertoli cell in the spermatogenic process. An impressive array of functions has been …

The Sertoli cell is thought to play a significant role in the hormonal regulation of
spermatogenesis within the rat testis. Little, however, is known about Sertoli cell function in …

Sertoli cells maintain dynamic and complex relationships with germinal cells in the
mammalian seminiferous tubule that are both spatial and functional in nature. As germinal …

The testis is composed of seminiferous tubules and interstitial tissue. The most important
component of the interstitial tissue are the testosterone-producing Leydig cells. The …

The “nurse cell” function of Sertoli cells in spermatogenesis was originally tacitly assumed
on the basis of the anatomical relationships between cells in the testis. In mammals, from …

The complex morphology of the Sertoli cells and their interactions with germ cells has been
a focus of investigators since they were first described by Enrico Sertoli. In the past 50 years …