Increased firing to cues that predict low-value reward in the medial orbitofrontal cortex

AC Burton, V Kashtelyan, DW Bryden… - Cerebral …, 2014 - academic.oup.com
Anatomical, imaging, and lesion work have suggested that medial and lateral aspects of
orbitofrontal cortex (OFC) play different roles in reward-guided decision-making, yet few …

Medial orbitofrontal neurons preferentially signal cues predicting changes in reward during unblocking

N Lopatina, MA McDannald, CV Styer… - Journal of …, 2016 - Soc Neuroscience
The orbitofrontal cortex (OFC) has been broadly implicated in the ability to use the current
value of expected outcomes to guide behavior. Although value correlates have been …

Rat orbitofrontal cortex separately encodes response and outcome information during performance of goal-directed behavior

T Furuyashiki, PC Holland… - Journal of Neuroscience, 2008 - Soc Neuroscience
Orbitofrontal cortex (OFC) neurons encode rewards and the cues that predict them,
providing a neural substrate for outcome expectancy, an important component of goal …

Cracking and packing information about the features of expected rewards in the orbitofrontal cortex

A Shimbo, YK Takahashi, AJ Langdon… - Journal of …, 2024 - jneurosci.org
The orbitofrontal cortex (OFC) is crucial for tracking various aspects of expected outcomes,
thereby helping to guide choices and support learning. Our previous study showed that the …

Functional heterogeneity within rat orbitofrontal cortex in reward learning and decision making

A Izquierdo - Journal of Neuroscience, 2017 - Soc Neuroscience
Rat orbitofrontal cortex (OFC) is located in the dorsal bank of the rhinal sulcus, and is
divided into the medial orbital area, ventral orbital area, ventrolateral orbital area, lateral …

Dissociable regulation of instrumental action within mouse prefrontal cortex

SL Gourley, AS Lee, JL Howell… - European Journal of …, 2010 - Wiley Online Library
Abstract Evaluation of the behavioral 'costs', such as effort expenditure relative to the
benefits of obtaining reward, is a major determinant of goal‐directed action. Neuroimaging …

Hedonic and informational functions of the human orbitofrontal cortex

R Elliott, Z Agnew, JFW Deakin - Cerebral Cortex, 2010 - academic.oup.com
Functional imaging studies have revealed roles for orbitofrontal cortex (OFC) in reward
processing and decision making. In many situations, rewards signal that the current …

The orbitofrontal cortex and response selection

JJ Young, ML Shapiro - Annals of the New York Academy of …, 2011 - Wiley Online Library
Orbitofrontal cortex (OFC) function is often characterized in terms of stimulus–reward
mapping; however, more recent evidence suggests that the OFC may play a role in selecting …

Dissociable effects of lesions to orbitofrontal cortex subregions on impulsive choice in the rat

AC Mar, ALJ Walker, DE Theobald… - Journal of …, 2011 - Soc Neuroscience
The orbitofrontal cortex (OFC) is implicated in a variety of adaptive decision-making
processes. Human studies suggest that there is a functional dissociation between medial …

Dissociating valence of outcome from behavioral control in human orbital and ventral prefrontal cortices

J O'Doherty, H Critchley, R Deichmann… - Journal of …, 2003 - Soc Neuroscience
The precise role of orbitofrontal cortex (OFC) in affective processing is still debated. One
view suggests OFC represents stimulus reward value and supports learning and relearning …