Introduction Whereas most studies focus on laboratory and clinical research, little is known
about the causes of death and risk factors for death in critically ill patients. Methods Three …

Abstract Introduction Kaplan–Meier curves and logistic models are widely used to describe
and explain the variability of survival in intensive care unit (ICU) patients. The Kaplan–Meier …

Background Acute lung injury (ALI) is a major cause of acute respiratory failure with high
mortality despite lung-protective ventilation. Prior work has shown disordered inflammation …

Introduction The aim of this study was to describe and compare the changes in ventilator
management and complications over time, as well as variables associated with 28-day …

Introduction Non-intensive care unit (ICU) cohorts have shown an association between
inflammatory disturbances and delirium, though these relationships have not been studied …

Background The incidence of sepsis can be estimated between 250 and 500 cases/100.000
people per year and is responsible for up to 6% of total hospital admissions. Identified as …

Introduction Due to the increasing burden on hospital systems, most elderly patients with
non-surgical sepsis are admitted to general internal medicine departments. Disease-severity …

Background The present study was performed to investigate the impacts of type 2 diabetes
mellitus (T2DM) on severe community-acquired pneumonia (SCAP) and to develop a novel …

Introduction The incidence and outcome of acute respiratory failure (ARF) depend on
dysfunction in other organs. As a result, reported mortality in patients with ARF is derived …

Introduction Non-neurological complications in patients with severe traumatic brain injury
(TBI) are frequent, worsening the prognosis, but the pathophysiology of systemic …