Is nicotine exposure linked to cardiopulmonary vulnerability to COVID‐19 in the general population?

JL Olds, N Kabbani - The FEBS journal, 2020 - Wiley Online Library
The recent emergence of COVID‐19 has resulted in a worldwide crisis, with large
populations locked down and transportation links severed. While approximately 80% of …

Nicotine upregulates ACE2 expression and increases competence for SARS-CoV-2 in human pneumocytes

F Maggi, A Rosellini, PG Spezia, D Focosi… - ERJ open …, 2021 - Eur Respiratory Soc
The coronavirus disease 2019 (COVID-19) pandemic has a variable degree of severity
according to underlying comorbidities and life-style. Several research groups have reported …

Beyond smoking cessation: investigating medicinal nicotine to prevent and treat COVID-19

HA Tindle, PA Newhouse… - Nicotine and Tobacco …, 2020 - academic.oup.com
In the absence of treatment or a vaccine, the SARS-CoV-2 pandemic challenges the medical
community to identify novel containment strategies. Changeux et al. 1 have proposed the …

COVID-19 and vaping: risk for increased susceptibility to SARS-CoV-2 infection?

KD McAlinden, MS Eapen, W Lu, C Chia… - European …, 2020 - Eur Respiratory Soc
With great interest we read and commend the study done by Russo et al.[1], highlighting
their findings that nicotine induces an increase in angiotensin-converting enzyme 2 (ACE-2) …

[PDF][PDF] Smoking and COVID-19: Scientific brief

World Health Organization - 2020 - escholarship.org
Background The harms of tobacco use are well-established. Tobacco causes 8 million
deaths every year from cardiovascular diseases, lung disorders, cancers, diabetes, and …

Smoking, ACE-2 and COVID-19: ongoing controversies

JM Leung, DD Sin - European Respiratory Journal, 2020 - Eur Respiratory Soc
The three letters from D. Lutchman, KD McAlinden and co-workers, and K. Farsalinos and co-
workers together capture the divergence in opinion on the impact of smoking on coronavirus …

Impact of tobacco smoking on the risk of COVID-19: a large scale retrospective cohort study

N Paleiron, A Mayet, V Marbac, A Perisse… - Nicotine and …, 2021 - academic.oup.com
Introduction Preliminary reports indicated that smokers could be less susceptible to
coronavirus SARS-CoV-2, which causes Covid-19. However, once infected an increased …

[HTML][HTML] Tobacco use as a well-recognized cause of severe COVID-19 manifestations

AK Gupta, ST Nethan, R Mehrotra - Respiratory Medicine, 2021 - Elsevier
Abstract Introduction The Coronavirus disease (COVID-19) infection is caused by the novel
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) primarily affecting the …

COVID-19 and smoking: is nicotine the hidden link?

P Russo, S Bonassi, R Giacconi… - European …, 2020 - Eur Respiratory Soc
Leung et al.[1] have recently published, in the European Respiratory Journal, a paper on the
expression of angiotensin-converting enzyme II (ACE-2) in the small airway epithelia of …

Tobacco product use and the risks of SARS-CoV-2 infection and COVID-19: current understanding and recommendations for future research

NL Benowitz, ML Goniewicz… - The Lancet …, 2022 - thelancet.com
Heterogeneity in the clinical presentation of SARS-CoV-2 infection and COVID-19
progression underscores the urgent need to identify individual-level susceptibility factors …