Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease

S Arlt, E Schwedhelm, H Kölsch, H Jahn… - Journal of …, 2012 - content.iospress.com
Dimethylarginine and homocysteine metabolism are closely linked and alterations of both
were observed in plasma and cerebrospinal fluid (CSF) of patients with Alzheimer's disease …

Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease

J Popp, P Lewczuk, M Linnebank… - Journal of …, 2009 - content.iospress.com
Disturbed homocysteine metabolism is a risk factor for Alzheimer's disease (AD) and may
contribute to the disease pathophysiology by increasing both amyloid-β (Aβ) production and …

Biochemical markers related to Alzheimer's dementia in serum and cerebrospinal fluid

CE Teunissen, J De Vente, HWM Steinbusch… - Neurobiology of …, 2002 - Elsevier
The diagnosis of Alzheimer's disease (AD) is currently based on clinical and
neuropsychological examination. To date there is no blood test available that can …

Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's …

ML Selley - Neurobiology of aging, 2003 - Elsevier
Vascular risk factors increase the risk of developing Alzheimer's disease. Increased
concentrations of circulating homocysteine are associated with an increased risk of both …

Cerebrospinal fluid amyloid beta, Tau levels, apolipoprotein, and 1H-MRS brain metabolites in Alzheimer's disease: a systematic review

AD Piersson, M Mohamad, F Rajab, S Suppiah - Academic Radiology, 2021 - Elsevier
Background There is compelling evidence that neurochemical changes measured by proton
magnetic resonance spectroscopy (1 H-MRS) occur at different phases of Alzheimer's …

One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond

L Dayon, SP Guiraud, J Corthésy, L Da Silva… - Alzheimer's research & …, 2017 - Springer
Background Hyperhomocysteinemia is a risk factor for cognitive decline and dementia,
including Alzheimer disease (AD). Homocysteine (Hcy) is a sulfur-containing amino acid …

Elevated S-adenosylhomocysteine in Alzheimer brain: influence on methyltransferases and cognitive function

BP Kennedy, T Bottiglieri, E Arning, MG Ziegler… - Journal of neural …, 2004 - Springer
Hyperhomocysteinemia is common in Alzheimer's disease and is negatively correlated with
cognitive function. Hyperhomocysteinemia can increase S-adenosylhomocysteine (SAH), a …

S-Adenosylmethionine Is Decreased in the Cerebrospinal Fluid of Patients with Alzheimer's Disease

M Linnebank, J Popp, Y Smulders, D Smith… - Neurodegenerative …, 2010 - karger.com
Background: Increased plasma homocysteine levels have been described as an
independent risk factor for Alzheimer's disease (AD), but the underlying pathophysiology is …

Cerebrospinal fluid and plasma biomarkers in neurodegenerative diseases

Y Seino, T Nakamura, T Kawarabayashi… - Journal of …, 2019 - content.iospress.com
Cerebrospinal fluid (CSF) amyloid-β (Aβ) 42 and tau are biomarkers for Alzheimer's disease
(AD); however, the effects of other neurodegenerative processes on these biomarkers …

CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status

R Dong, BF Darst, Y Deming, Y Ma, Q Lu… - Alzheimer's & …, 2021 - Wiley Online Library
Introduction Cerebrospinal fluid (CSF) total tau (t‐tau) and phosphorylated tau (p‐tau) are
biomarkers of Alzheimer's disease (AD), yet much is unknown about AD‐associated …